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GO:0004713 protein tyrosine kinase activity

Term Information

ID GO:0004713
Name protein tyrosine kinase activity
Ontology Molecular Function
Definition Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
Secondary IDs GO:0004718
GONUTS GO:0004713 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact protein-tyrosine kinase activity
narrow JAK
narrow Janus kinase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.10
InterPro IPR005189
InterPro IPR016250
InterPro IPR020635
InterPro IPR020691
InterPro IPR026984
InterPro IPR028459
InterPro IPR028539
InterPro IPR030118
InterPro IPR030220
UniProtKB-KW Tyrosine-protein kinase

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0004717 focal adhesion kinase activity REPLACEDBY GO:0004713

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004713:
Relationship To GO:0004713 Child Term Child Term Name
Is a GO:0004714 transmembrane receptor protein tyrosine kinase activity
Is a GO:0004715 non-membrane spanning protein tyrosine kinase activity
Is a GO:0004716 receptor signaling protein tyrosine kinase activity
Regulates GO:0061097 regulation of protein tyrosine kinase activity
Positively regulates GO:0061098 positive regulation of protein tyrosine kinase activity
Negatively regulates GO:0061099 negative regulation of protein tyrosine kinase activity
Is a GO:0035400 histone tyrosine kinase activity
Is a GO:0097469 cyclin-dependent protein tyrosine kinase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004713. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004713 based on the entire annotation set Co-occurrence statistics for GO:0004713 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-10-10 Added RELATION part of GO:0018108 (peptidyl-tyrosine phosphorylation)
2011-04-18 Deleted XREF MetaCyc:EC-2.7.10
2010-10-08 Added XREF MetaCyc:EC-2.7.10
2010-10-08 Deleted XREF EC:2.7.11.-
2010-10-08 Deleted XREF MetaCyc:2.7.10.2-RXN
2010-10-08 Deleted XREF MetaCyc:2.7.10.1-RXN
2010-10-07 Added SYNONYM Janus kinase activity
2010-10-07 Added SECONDARY GO:0004718 (Janus kinase activity)
2010-10-07 Added XREF EC:2.7.11.-
2010-10-07 Added SYNONYM JAK
2009-05-21 Deleted XREF MetaCyc:PROTEIN-TYROSINE-KINASE-RXN
2009-05-21 Added XREF MetaCyc:2.7.10.2-RXN
2009-05-21 Added XREF MetaCyc:2.7.10.1-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
2008-05-01 Updated TERM protein tyrosine kinase activity
2008-05-01 Deleted SYNONYM protein tyrosine kinase activity
2008-05-01 Added SYNONYM protein-tyrosine kinase activity
2008-04-01 Updated RELATION is a GO:0004672 (protein kinase activity)
2007-09-13 Added XREF EC:2.7.10
2007-09-13 Deleted XREF EC:2.7.1.112
2007-09-10 Deleted SYNONYM focal adhesion kinase activity
2007-08-09 Added SYNONYM focal adhesion kinase activity
2007-08-09 Added SYNONYM protein tyrosine kinase activity
2007-08-09 Deleted SYNONYM focal adhesion kinase activity
2007-08-09 Deleted SYNONYM protein tyrosine kinase activity
2005-08-10 Added SYNONYM focal adhesion kinase activity
2004-09-23 Added SYNONYM protein tyrosine kinase activity
2003-10-27 Added XREF MetaCyc:PROTEIN-TYROSINE-KINASE-RXN
2003-09-09 Updated TERM protein-tyrosine kinase activity
2003-03-19 Updated TERM protein tyrosine kinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
2002-02-06 Updated TERM protein tyrosine kinase
2001-04-03 Updated TERM protein tyrosine kinase
2001-03-30 Added XREF EC:2.7.1.112
2001-03-30 Added TERM protein tyrosine kinase

Term

Timestamp Action Category Detail
2008-05-01 Updated TERM protein tyrosine kinase activity
2003-09-09 Updated TERM protein-tyrosine kinase activity
2003-03-19 Updated TERM protein tyrosine kinase activity
2002-02-06 Updated TERM protein tyrosine kinase
2001-04-03 Updated TERM protein tyrosine kinase
2001-03-30 Added TERM protein tyrosine kinase

Definition/synonyms

Timestamp Action Category Detail
2010-10-07 Added SYNONYM Janus kinase activity
2010-10-07 Added SYNONYM JAK
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
2008-05-01 Deleted SYNONYM protein tyrosine kinase activity
2008-05-01 Added SYNONYM protein-tyrosine kinase activity
2007-09-10 Deleted SYNONYM focal adhesion kinase activity
2007-08-09 Added SYNONYM focal adhesion kinase activity
2007-08-09 Added SYNONYM protein tyrosine kinase activity
2007-08-09 Deleted SYNONYM focal adhesion kinase activity
2007-08-09 Deleted SYNONYM protein tyrosine kinase activity
2005-08-10 Added SYNONYM focal adhesion kinase activity
2004-09-23 Added SYNONYM protein tyrosine kinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.

Relationships

Timestamp Action Category Detail
2013-10-10 Added RELATION part of GO:0018108 (peptidyl-tyrosine phosphorylation)
2008-04-01 Updated RELATION is a GO:0004672 (protein kinase activity)

Cross-references

Timestamp Action Category Detail
2011-04-18 Deleted XREF MetaCyc:EC-2.7.10
2010-10-08 Added XREF MetaCyc:EC-2.7.10
2010-10-08 Deleted XREF EC:2.7.11.-
2010-10-08 Deleted XREF MetaCyc:2.7.10.2-RXN
2010-10-08 Deleted XREF MetaCyc:2.7.10.1-RXN
2010-10-07 Added XREF EC:2.7.11.-
2009-05-21 Deleted XREF MetaCyc:PROTEIN-TYROSINE-KINASE-RXN
2009-05-21 Added XREF MetaCyc:2.7.10.2-RXN
2009-05-21 Added XREF MetaCyc:2.7.10.1-RXN
2007-09-13 Added XREF EC:2.7.10
2007-09-13 Deleted XREF EC:2.7.1.112
2003-10-27 Added XREF MetaCyc:PROTEIN-TYROSINE-KINASE-RXN
2001-03-30 Added XREF EC:2.7.1.112

Other

Timestamp Action Category Detail
2010-10-07 Added SECONDARY GO:0004718 (Janus kinase activity)
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