spacer

GO:0004697 protein kinase C activity

Term Information

ID GO:0004697
Name protein kinase C activity
Ontology Molecular Function
Definition Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
Secondary IDs GO:0004701
GONUTS GO:0004697 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact ATP:protein phosphotransferase (diacylglycerol-dependent) activity
related PKC
related PKCalpha
related PKCbeta
related PKCdelta
related PKCepsilon
related PKCgamma
related PKCzeta
related Pkc1p
related STK24
related cPKC
related cPKCalpha
related cPKCbeta
related cPKCgamma
related nPKC
related nPKCdelta
related nPKCepsilon
related nPKCeta
related nPKCtheta
narrow protein kinase Cepsilon activity
exact diacylglycerol-activated phospholipid-dependent PKC activity
exact diacylglycerol-activated phospholipid-dependent protein kinase C activity
exact PKC activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.11.13
InterPro IPR014375
InterPro IPR014376
InterPro IPR015727
InterPro IPR027264
InterPro IPR027431
InterPro IPR027436
MetaCyc 2.7.11.13-RXN

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004697:
Relationship To GO:0004697 Child Term Child Term Name
Negatively regulates GO:0008426 protein kinase C inhibitor activity
Is a GO:0004698 calcium-dependent protein kinase C activity
Is a GO:0004699 calcium-independent protein kinase C activity
Regulates GO:1900019 regulation of protein kinase C activity
Positively regulates GO:1900020 positive regulation of protein kinase C activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004697. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004697 based on the entire annotation set Co-occurrence statistics for GO:0004697 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2010-09-24 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
2009-05-21 Added XREF MetaCyc:2.7.11.13-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2008-04-01 Updated RELATION is a GO:0001565 (phorbol ester receptor activity)
2008-04-01 Deleted RELATION is a GO:0001565 (phorbol ester receptor activity)
2008-04-01 Updated RELATION is a GO:0004674 (protein serine/threonine kinase activity)
2008-04-01 Deleted SYNONYM protein kinase C activity
2007-11-08 Added SYNONYM ATP:protein phosphotransferase (diacylglycerol-dependent) activity
2007-11-08 Added SYNONYM PKC
2007-11-08 Added SYNONYM PKCalpha
2007-11-08 Added SYNONYM PKCbeta
2007-11-08 Added SYNONYM PKCdelta
2007-11-08 Added SYNONYM PKCepsilon
2007-11-08 Added SYNONYM PKCgamma
2007-11-08 Added SYNONYM PKCzeta
2007-11-08 Added SYNONYM Pkc1p
2007-11-08 Added SYNONYM STK24
2007-11-08 Added SYNONYM cPKC
2007-11-08 Added SYNONYM cPKCalpha
2007-11-08 Added SYNONYM cPKCbeta
2007-11-08 Added SYNONYM cPKCgamma
2007-11-08 Added SYNONYM nPKC
2007-11-08 Added SYNONYM nPKCdelta
2007-11-08 Added SYNONYM nPKCepsilon
2007-11-08 Added SYNONYM nPKCeta
2007-11-08 Added SYNONYM nPKCtheta
2007-11-08 Added SYNONYM protein kinase C activity
2007-11-08 Added SYNONYM protein kinase Cepsilon activity
2007-10-25 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2007-09-26 Added SECONDARY GO:0004701 (diacylglycerol-activated phospholipid-dependent protein kinase C activity)
2007-09-26 Added XREF EC:2.7.11.13
2007-09-26 Deleted XREF EC:2.7.1.-
2007-09-26 Added SYNONYM diacylglycerol-activated phospholipid-dependent PKC activity
2007-09-26 Added SYNONYM diacylglycerol-activated phospholipid-dependent protein kinase C activity
2007-08-09 Added SYNONYM PKC activity
2007-08-09 Deleted SYNONYM PKC activity
2005-07-29 Deleted SYNONYM PKC
2005-07-29 Added SYNONYM PKC activity
2004-04-19 Added SYNONYM PKC
2004-04-16 Deleted SYNONYM PKC
2003-03-19 Updated TERM protein kinase C activity
2002-02-06 Updated TERM protein kinase C
2001-04-03 Updated TERM protein kinase C
2001-03-30 Added XREF EC:2.7.1.-
2001-03-30 Added SYNONYM PKC
2001-03-30 Added TERM protein kinase C

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM protein kinase C activity
2002-02-06 Updated TERM protein kinase C
2001-04-03 Updated TERM protein kinase C
2001-03-30 Added TERM protein kinase C

Definition/synonyms

Timestamp Action Category Detail
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2010-09-24 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2008-04-01 Deleted SYNONYM protein kinase C activity
2007-11-08 Added SYNONYM ATP:protein phosphotransferase (diacylglycerol-dependent) activity
2007-11-08 Added SYNONYM PKC
2007-11-08 Added SYNONYM PKCalpha
2007-11-08 Added SYNONYM PKCbeta
2007-11-08 Added SYNONYM PKCdelta
2007-11-08 Added SYNONYM PKCepsilon
2007-11-08 Added SYNONYM PKCgamma
2007-11-08 Added SYNONYM PKCzeta
2007-11-08 Added SYNONYM Pkc1p
2007-11-08 Added SYNONYM STK24
2007-11-08 Added SYNONYM cPKC
2007-11-08 Added SYNONYM cPKCalpha
2007-11-08 Added SYNONYM cPKCbeta
2007-11-08 Added SYNONYM cPKCgamma
2007-11-08 Added SYNONYM nPKC
2007-11-08 Added SYNONYM nPKCdelta
2007-11-08 Added SYNONYM nPKCepsilon
2007-11-08 Added SYNONYM nPKCeta
2007-11-08 Added SYNONYM nPKCtheta
2007-11-08 Added SYNONYM protein kinase C activity
2007-11-08 Added SYNONYM protein kinase Cepsilon activity
2007-10-25 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol.
2007-09-26 Added SYNONYM diacylglycerol-activated phospholipid-dependent PKC activity
2007-09-26 Added SYNONYM diacylglycerol-activated phospholipid-dependent protein kinase C activity
2007-08-09 Added SYNONYM PKC activity
2007-08-09 Deleted SYNONYM PKC activity
2005-07-29 Deleted SYNONYM PKC
2005-07-29 Added SYNONYM PKC activity
2004-04-19 Added SYNONYM PKC
2004-04-16 Deleted SYNONYM PKC
2001-03-30 Added SYNONYM PKC

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0001565 (phorbol ester receptor activity)
2008-04-01 Deleted RELATION is a GO:0001565 (phorbol ester receptor activity)
2008-04-01 Updated RELATION is a GO:0004674 (protein serine/threonine kinase activity)

Cross-references

Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:2.7.11.13-RXN
2007-09-26 Added XREF EC:2.7.11.13
2007-09-26 Deleted XREF EC:2.7.1.-
2001-03-30 Added XREF EC:2.7.1.-

Other

Timestamp Action Category Detail
2007-09-26 Added SECONDARY GO:0004701 (diacylglycerol-activated phospholipid-dependent protein kinase C activity)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
16ms