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GO:0004691 cAMP-dependent protein kinase activity

Term Information

ID GO:0004691
Name cAMP-dependent protein kinase activity
Ontology Molecular Function
Definition Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cAMP.
Secondary IDs GO:0008602
GONUTS GO:0004691 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact ATP:protein phosphotransferase (cAMP-dependent) activity
related PKA C
related STK22
broad protein kinase A activity
related AMPK
exact cAMP-dependent protein kinase, intrinsic catalyst activity
exact 3',5'-cAMP-dependent protein kinase activity
exact adenosine 3',5'-cyclophosphate-dependent protein kinase activity
related PKA
exact cyclic AMP-dependent protein kinase activity
exact 3',5' cAMP-dependent protein kinase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.11.11
InterPro IPR028852
MetaCyc 2.7.11.11-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004691:
Relationship To GO:0004691 Child Term Child Term Name
Negatively regulates GO:0004862 cAMP-dependent protein kinase inhibitor activity
Regulates GO:0008603 cAMP-dependent protein kinase regulator activity
Negatively regulates GO:2000480 negative regulation of cAMP-dependent protein kinase activity
Regulates GO:2000479 regulation of cAMP-dependent protein kinase activity
Positively regulates GO:2000481 positive regulation of cAMP-dependent protein kinase activity
Capable of GO:0005952 cAMP-dependent protein kinase complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004691. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004691 based on the entire annotation set Co-occurrence statistics for GO:0004691 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-24 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cAMP.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2009-05-21 Added XREF MetaCyc:2.7.11.11-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2008-04-01 Updated RELATION is a GO:0004690 (cyclic nucleotide-dependent protein kinase activity)
2008-04-01 Deleted SYNONYM cAMP-dependent protein kinase activity
2007-11-08 Added SYNONYM AMPK
2007-11-08 Added SYNONYM ATP:protein phosphotransferase (cAMP-dependent) activity
2007-11-08 Added SYNONYM PKA
2007-11-08 Added SYNONYM PKA C
2007-11-08 Added SYNONYM STK22
2007-11-08 Added SYNONYM cAMP-dependent protein kinase activity
2007-11-08 Added SYNONYM protein kinase A activity
2007-11-08 Deleted SYNONYM PKA
2007-09-26 Added XREF EC:2.7.11.11
2007-08-09 Added SYNONYM 3',5'-cAMP-dependent protein kinase activity
2007-08-09 Added SYNONYM PKA
2007-08-09 Added SYNONYM adenosine 3',5'-cyclophosphate-dependent protein kinase activity
2007-08-09 Added SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2007-08-09 Added SYNONYM cyclic AMP-dependent protein kinase activity
2007-08-09 Added SYNONYM 3',5' cAMP-dependent protein kinase activity
2007-08-09 Deleted SYNONYM 3',5' cAMP-dependent protein kinase activity
2007-08-09 Deleted SYNONYM 3',5'-cAMP-dependent protein kinase activity
2007-08-09 Deleted SYNONYM PKA
2007-08-09 Deleted SYNONYM adenosine 3',5'-cyclophosphate-dependent protein kinase activity
2007-08-09 Deleted SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2007-08-09 Deleted SYNONYM cyclic AMP-dependent protein kinase activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2005-12-26 Added SYNONYM 3',5' cAMP-dependent protein kinase activity
2005-12-26 Added SYNONYM 3',5'-cAMP-dependent protein kinase activity
2005-12-26 Added SYNONYM adenosine 3',5'-cyclophosphate-dependent protein kinase activity
2005-12-26 Added SYNONYM cyclic AMP-dependent protein kinase activity
2004-04-19 Added SYNONYM PKA
2004-04-19 Added SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2004-04-16 Deleted SYNONYM PKA
2004-04-16 Deleted SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2003-12-20 Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, dependent on the presence of cAMP.
2003-12-20 Added SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2003-12-20 Added SECONDARY GO:0008602 (cAMP-dependent protein kinase, intrinsic catalyst activity)
2003-11-05 Deleted XREF MetaCyc:PROTEIN-KINASE-RXN
2003-11-05 Deleted XREF EC:2.7.1.37
2003-10-27 Added SYNONYM PKA
2003-10-27 Added XREF MetaCyc:PROTEIN-KINASE-RXN
2003-08-21 Deleted SYNONYM PKA
2003-03-19 Updated TERM cAMP-dependent protein kinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
2002-06-12 Added XREF EC:2.7.1.37
2002-06-12 Deleted XREF EC:2.7.1.-
2002-02-06 Updated TERM cAMP-dependent protein kinase
2001-04-03 Updated TERM cAMP-dependent protein kinase
2001-03-30 Added XREF EC:2.7.1.-
2001-03-30 Added SYNONYM PKA
2001-03-30 Added TERM cAMP-dependent protein kinase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM cAMP-dependent protein kinase activity
2002-02-06 Updated TERM cAMP-dependent protein kinase
2001-04-03 Updated TERM cAMP-dependent protein kinase
2001-03-30 Added TERM cAMP-dependent protein kinase

Definition/synonyms

Timestamp Action Category Detail
2010-09-24 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cAMP.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2008-04-01 Deleted SYNONYM cAMP-dependent protein kinase activity
2007-11-08 Added SYNONYM AMPK
2007-11-08 Added SYNONYM ATP:protein phosphotransferase (cAMP-dependent) activity
2007-11-08 Added SYNONYM PKA
2007-11-08 Added SYNONYM PKA C
2007-11-08 Added SYNONYM STK22
2007-11-08 Added SYNONYM cAMP-dependent protein kinase activity
2007-11-08 Added SYNONYM protein kinase A activity
2007-11-08 Deleted SYNONYM PKA
2007-08-09 Added SYNONYM 3',5'-cAMP-dependent protein kinase activity
2007-08-09 Added SYNONYM PKA
2007-08-09 Added SYNONYM adenosine 3',5'-cyclophosphate-dependent protein kinase activity
2007-08-09 Added SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2007-08-09 Added SYNONYM cyclic AMP-dependent protein kinase activity
2007-08-09 Added SYNONYM 3',5' cAMP-dependent protein kinase activity
2007-08-09 Deleted SYNONYM 3',5' cAMP-dependent protein kinase activity
2007-08-09 Deleted SYNONYM 3',5'-cAMP-dependent protein kinase activity
2007-08-09 Deleted SYNONYM PKA
2007-08-09 Deleted SYNONYM adenosine 3',5'-cyclophosphate-dependent protein kinase activity
2007-08-09 Deleted SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2007-08-09 Deleted SYNONYM cyclic AMP-dependent protein kinase activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2005-12-26 Added SYNONYM 3',5' cAMP-dependent protein kinase activity
2005-12-26 Added SYNONYM 3',5'-cAMP-dependent protein kinase activity
2005-12-26 Added SYNONYM adenosine 3',5'-cyclophosphate-dependent protein kinase activity
2005-12-26 Added SYNONYM cyclic AMP-dependent protein kinase activity
2004-04-19 Added SYNONYM PKA
2004-04-19 Added SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2004-04-16 Deleted SYNONYM PKA
2004-04-16 Deleted SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2003-12-20 Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, dependent on the presence of cAMP.
2003-12-20 Added SYNONYM cAMP-dependent protein kinase, intrinsic catalyst activity
2003-10-27 Added SYNONYM PKA
2003-08-21 Deleted SYNONYM PKA
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
2001-03-30 Added SYNONYM PKA

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004690 (cyclic nucleotide-dependent protein kinase activity)

Cross-references

Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:2.7.11.11-RXN
2007-09-26 Added XREF EC:2.7.11.11
2003-11-05 Deleted XREF MetaCyc:PROTEIN-KINASE-RXN
2003-11-05 Deleted XREF EC:2.7.1.37
2003-10-27 Added XREF MetaCyc:PROTEIN-KINASE-RXN
2002-06-12 Added XREF EC:2.7.1.37
2002-06-12 Deleted XREF EC:2.7.1.-
2001-03-30 Added XREF EC:2.7.1.-

Other

Timestamp Action Category Detail
2003-12-20 Added SECONDARY GO:0008602 (cAMP-dependent protein kinase, intrinsic catalyst activity)
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