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GO:0004683 calmodulin-dependent protein kinase activity

Term Information

ID GO:0004683
Name calmodulin-dependent protein kinase activity
Ontology Molecular Function
Definition Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.
PMID:11264466
Secondary IDs GO:0004684 GO:0004685 GO:0004688
GONUTS GO:0004683 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow Ca2+/calmodulin-dependent protein kinase kinase beta activity
narrow CaM kinase II activity
exact CaM-regulated serine/threonine kinase activity
related CaMKI
related CaMKII
related CaMKIV
related CaMKKalpha
related CaMKKbeta
related STK20
narrow calcium/calmodulin-dependent protein kinase type II activity
narrow caldesmon kinase (phosphorylating) activity
narrow calmodulin-dependent kinase II activity
related microtubule-associated protein 2 kinase activity
related multifunctional calcium/calmodulin regulated protein kinase activity
exact Ca2+/CaM-dependent kinase activity
exact CaM kinase activity
exact calcium- and calmodulin-dependent protein kinase activity
exact calcium/calmodulin-dependent protein kinase activity
exact calmodulin regulated protein kinase activity
narrow calmodulin-dependent protein kinase I activity
related multifunctional calcium- and calmodulin-regulated protein kinase activity
exact ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity
related CAM PKII
narrow Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity
narrow Ca2+/calmodulin-dependent protein kinase 1 activity
narrow Ca2+/calmodulin-dependent protein kinase II activity
narrow Ca2+/calmodulin-dependent protein kinase IV activity
exact Ca2+/calmodulin-dependent protein kinase activity
narrow Ca2+/calmodulin-dependent protein kinase kinase activity
narrow ATP:caldesmon O-phosphotransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.11.17
InterPro IPR013543
MetaCyc 2.7.11.17-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004683:
Relationship To GO:0004683 Child Term Child Term Name
Is a GO:0016905 myosin heavy chain kinase activity
Is a GO:0004686 elongation factor-2 kinase activity
Is a GO:0004689 phosphorylase kinase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Date
Assigned By
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Name
Synonym
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004683. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004683 based on the entire annotation set Co-occurrence statistics for GO:0004683 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2010-09-24 Added DEFINITION Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2008-04-05 Deleted SYNONYM caldesmon kinase activity
2008-04-01 Updated RELATION is a GO:0004674 (protein serine/threonine kinase activity)
2007-11-08 Added SYNONYM ATP:caldesmon O-phosphotransferase activity
2007-11-08 Added SYNONYM ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity
2007-11-08 Added SYNONYM CAM PKII
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase 1 activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase II activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase IV activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase kinase activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase kinase beta activity
2007-11-08 Added SYNONYM CaM kinase II activity
2007-11-08 Added SYNONYM CaM-regulated serine/threonine kinase activity
2007-11-08 Added SYNONYM CaMKI
2007-11-08 Added SYNONYM CaMKII
2007-11-08 Added SYNONYM CaMKIV
2007-11-08 Added SYNONYM CaMKKalpha
2007-11-08 Added SYNONYM CaMKKbeta
2007-11-08 Added SYNONYM STK20
2007-11-08 Added SYNONYM calcium/calmodulin-dependent protein kinase type II activity
2007-11-08 Added SYNONYM caldesmon kinase (phosphorylating) activity
2007-11-08 Added SYNONYM caldesmon kinase activity
2007-11-08 Added SYNONYM calmodulin-dependent kinase II activity
2007-11-08 Added SYNONYM microtubule-associated protein 2 kinase activity
2007-11-08 Added SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-11-08 Deleted SYNONYM CaMKI
2007-11-08 Deleted SYNONYM CaMKII
2007-11-08 Deleted SYNONYM CaMKIV
2007-11-08 Deleted SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-09-26 Added XREF MetaCyc:2.7.11.17-RXN
2007-09-26 Added XREF EC:2.7.11.17
2007-09-26 Deleted XREF EC:2.7.1.-
2007-09-26 Deleted XREF MetaCyc:2.7.1.123-RXN
2007-09-26 Deleted XREF EC:2.7.1.123
2007-08-09 Added SYNONYM Ca2+/CaM-dependent kinase activity
2007-08-09 Added SYNONYM CaM kinase activity
2007-08-09 Added SYNONYM CaMKI
2007-08-09 Added SYNONYM CaMKII
2007-08-09 Added SYNONYM CaMKIV
2007-08-09 Added SYNONYM calcium- and calmodulin-dependent protein kinase activity
2007-08-09 Added SYNONYM calcium/calmodulin-dependent protein kinase activity
2007-08-09 Added SYNONYM calmodulin regulated protein kinase activity
2007-08-09 Added SYNONYM calmodulin-dependent protein kinase I activity
2007-08-09 Added SYNONYM multifunctional calcium- and calmodulin-regulated protein kinase activity
2007-08-09 Added SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-08-09 Deleted SYNONYM CaMKI
2007-08-09 Deleted SYNONYM CaMKII
2007-08-09 Deleted SYNONYM CaMKIV
2007-08-09 Deleted SYNONYM calcium- and calmodulin-dependent protein kinase activity
2007-08-09 Deleted SYNONYM calcium/calmodulin-dependent protein kinase activity
2007-08-09 Deleted SYNONYM calmodulin regulated protein kinase activity
2007-08-09 Deleted SYNONYM calmodulin-dependent protein kinase I activity
2007-08-09 Deleted SYNONYM multifunctional calcium- and calmodulin-regulated protein kinase activity
2007-08-09 Deleted SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-08-09 Deleted SYNONYM Ca2+/CaM-dependent kinase activity
2007-08-09 Deleted SYNONYM CaM kinase activity
2007-05-27 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2007-05-07 Added SYNONYM Ca2+/CaM-dependent kinase activity
2007-05-07 Added SYNONYM CaM kinase activity
2007-05-07 Added SYNONYM CaMKI
2007-05-07 Added SYNONYM CaMKII
2007-05-07 Added SYNONYM CaMKIV
2007-05-07 Added SYNONYM calcium- and calmodulin-dependent protein kinase activity
2007-05-07 Added SYNONYM calcium/calmodulin-dependent protein kinase activity
2007-05-07 Added SYNONYM calmodulin regulated protein kinase activity
2007-05-07 Added SYNONYM calmodulin-dependent protein kinase I activity
2007-05-07 Added SYNONYM multifunctional calcium- and calmodulin-regulated protein kinase activity
2007-05-07 Added SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-05-07 Added SECONDARY GO:0004688 (multifunctional calcium- and calmodulin-regulated protein kinase activity)
2007-05-07 Added SECONDARY GO:0004685 (calcium- and calmodulin-dependent protein kinase activity)
2007-05-07 Added SECONDARY GO:0004684 (calmodulin-dependent protein kinase I activity)
2007-05-07 Added XREF MetaCyc:2.7.1.123-RXN
2007-05-07 Added XREF EC:2.7.1.123
2007-05-07 Updated TERM calmodulin-dependent protein kinase activity
2003-03-19 Updated TERM calmodulin regulated protein kinase activity
2002-02-06 Updated TERM calmodulin regulated protein kinase
2001-04-03 Updated TERM calmodulin regulated protein kinase
2001-03-30 Added XREF EC:2.7.1.-
2001-03-30 Added TERM calmodulin regulated protein kinase

Term

Timestamp Action Category Detail
2007-05-07 Updated TERM calmodulin-dependent protein kinase activity
2003-03-19 Updated TERM calmodulin regulated protein kinase activity
2002-02-06 Updated TERM calmodulin regulated protein kinase
2001-04-03 Updated TERM calmodulin regulated protein kinase
2001-03-30 Added TERM calmodulin regulated protein kinase

Definition/synonyms

Timestamp Action Category Detail
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2010-09-24 Added DEFINITION Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2008-04-05 Deleted SYNONYM caldesmon kinase activity
2007-11-08 Added SYNONYM ATP:caldesmon O-phosphotransferase activity
2007-11-08 Added SYNONYM ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity
2007-11-08 Added SYNONYM CAM PKII
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase 1 activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase II activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase IV activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase kinase activity
2007-11-08 Added SYNONYM Ca2+/calmodulin-dependent protein kinase kinase beta activity
2007-11-08 Added SYNONYM CaM kinase II activity
2007-11-08 Added SYNONYM CaM-regulated serine/threonine kinase activity
2007-11-08 Added SYNONYM CaMKI
2007-11-08 Added SYNONYM CaMKII
2007-11-08 Added SYNONYM CaMKIV
2007-11-08 Added SYNONYM CaMKKalpha
2007-11-08 Added SYNONYM CaMKKbeta
2007-11-08 Added SYNONYM STK20
2007-11-08 Added SYNONYM calcium/calmodulin-dependent protein kinase type II activity
2007-11-08 Added SYNONYM caldesmon kinase (phosphorylating) activity
2007-11-08 Added SYNONYM caldesmon kinase activity
2007-11-08 Added SYNONYM calmodulin-dependent kinase II activity
2007-11-08 Added SYNONYM microtubule-associated protein 2 kinase activity
2007-11-08 Added SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-11-08 Deleted SYNONYM CaMKI
2007-11-08 Deleted SYNONYM CaMKII
2007-11-08 Deleted SYNONYM CaMKIV
2007-11-08 Deleted SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-08-09 Added SYNONYM Ca2+/CaM-dependent kinase activity
2007-08-09 Added SYNONYM CaM kinase activity
2007-08-09 Added SYNONYM CaMKI
2007-08-09 Added SYNONYM CaMKII
2007-08-09 Added SYNONYM CaMKIV
2007-08-09 Added SYNONYM calcium- and calmodulin-dependent protein kinase activity
2007-08-09 Added SYNONYM calcium/calmodulin-dependent protein kinase activity
2007-08-09 Added SYNONYM calmodulin regulated protein kinase activity
2007-08-09 Added SYNONYM calmodulin-dependent protein kinase I activity
2007-08-09 Added SYNONYM multifunctional calcium- and calmodulin-regulated protein kinase activity
2007-08-09 Added SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-08-09 Deleted SYNONYM CaMKI
2007-08-09 Deleted SYNONYM CaMKII
2007-08-09 Deleted SYNONYM CaMKIV
2007-08-09 Deleted SYNONYM calcium- and calmodulin-dependent protein kinase activity
2007-08-09 Deleted SYNONYM calcium/calmodulin-dependent protein kinase activity
2007-08-09 Deleted SYNONYM calmodulin regulated protein kinase activity
2007-08-09 Deleted SYNONYM calmodulin-dependent protein kinase I activity
2007-08-09 Deleted SYNONYM multifunctional calcium- and calmodulin-regulated protein kinase activity
2007-08-09 Deleted SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity
2007-08-09 Deleted SYNONYM Ca2+/CaM-dependent kinase activity
2007-08-09 Deleted SYNONYM CaM kinase activity
2007-05-27 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin.
2007-05-07 Added SYNONYM Ca2+/CaM-dependent kinase activity
2007-05-07 Added SYNONYM CaM kinase activity
2007-05-07 Added SYNONYM CaMKI
2007-05-07 Added SYNONYM CaMKII
2007-05-07 Added SYNONYM CaMKIV
2007-05-07 Added SYNONYM calcium- and calmodulin-dependent protein kinase activity
2007-05-07 Added SYNONYM calcium/calmodulin-dependent protein kinase activity
2007-05-07 Added SYNONYM calmodulin regulated protein kinase activity
2007-05-07 Added SYNONYM calmodulin-dependent protein kinase I activity
2007-05-07 Added SYNONYM multifunctional calcium- and calmodulin-regulated protein kinase activity
2007-05-07 Added SYNONYM multifunctional calcium/calmodulin regulated protein kinase activity

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004674 (protein serine/threonine kinase activity)

Cross-references

Timestamp Action Category Detail
2007-09-26 Added XREF MetaCyc:2.7.11.17-RXN
2007-09-26 Added XREF EC:2.7.11.17
2007-09-26 Deleted XREF EC:2.7.1.-
2007-09-26 Deleted XREF MetaCyc:2.7.1.123-RXN
2007-09-26 Deleted XREF EC:2.7.1.123
2007-05-07 Added XREF MetaCyc:2.7.1.123-RXN
2007-05-07 Added XREF EC:2.7.1.123
2001-03-30 Added XREF EC:2.7.1.-

Other

Timestamp Action Category Detail
2007-05-07 Added SECONDARY GO:0004688 (multifunctional calcium- and calmodulin-regulated protein kinase activity)
2007-05-07 Added SECONDARY GO:0004685 (calcium- and calmodulin-dependent protein kinase activity)
2007-05-07 Added SECONDARY GO:0004684 (calmodulin-dependent protein kinase I activity)
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