spacer

GO:0004675 transmembrane receptor protein serine/threonine kinase activity

Term Information

ID GO:0004675
Name transmembrane receptor protein serine/threonine kinase activity
Ontology Molecular Function
Definition Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GONUTS GO:0004675 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow activin receptor kinase activity
narrow receptor type I serine/threonine protein kinase activity
exact receptor serine/threonine protein kinase activity
exact receptor protein serine/threonine kinase activity
narrow receptor type II serine/threonine protein kinase activity
exact ATP:receptor-protein phosphotransferase activity
related STK13
narrow TGF-beta kinase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.11.-
InterPro IPR000472
InterPro IPR003605
InterPro IPR015771
MetaCyc 2.7.11.30-RXN

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004675:
Relationship To GO:0004675 Child Term Child Term Name
Is a GO:0005024 transforming growth factor beta-activated receptor activity
Is a GO:0017002 activin-activated receptor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004675. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004675 based on the entire annotation set Co-occurrence statistics for GO:0004675 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-02-18 Added RELATION part of GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway)
2011-02-15 Added RELATION is a GO:0004674 (protein serine/threonine kinase activity)
2011-01-30 Deleted DEFINITION Catalysis of the reaction: ATP + transmembrane receptor protein serine = ADP + transmembrane receptor protein serine phosphate, and ATP + transmembrane receptor protein threonine = ADP + transmembrane receptor protein threonine phosphate.
2011-01-30 Added DEFINITION Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2010-11-04 Deleted RELATION is a GO:0004702 (receptor signaling protein serine/threonine kinase activity)
2010-09-24 Added DEFINITION Catalysis of the reaction: ATP + transmembrane receptor protein serine = ADP + transmembrane receptor protein serine phosphate, and ATP + transmembrane receptor protein threonine = ADP + transmembrane receptor protein threonine phosphate.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.
2009-05-21 Added XREF MetaCyc:2.7.11.30-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.
2008-04-01 Updated RELATION is a GO:0019199 (transmembrane receptor protein kinase activity)
2008-04-01 Updated RELATION is a GO:0004702 (receptor signaling protein serine/threonine kinase activity)
2007-11-08 Added SYNONYM ATP:receptor-protein phosphotransferase activity
2007-11-08 Added SYNONYM STK13
2007-11-08 Added SYNONYM TGF-beta kinase activity
2007-11-08 Added SYNONYM activin receptor kinase activity
2007-11-08 Added SYNONYM receptor protein serine/threonine kinase activity
2007-11-08 Added SYNONYM receptor serine/threonine protein kinase activity
2007-11-08 Added SYNONYM receptor type I serine/threonine protein kinase activity
2007-11-08 Added SYNONYM receptor type II serine/threonine protein kinase activity
2007-10-25 Added DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.
2007-09-26 Added XREF EC:2.7.11.-
2007-09-26 Deleted XREF EC:2.7.1.-
2003-03-19 Updated TERM transmembrane receptor protein serine/threonine kinase activity
2002-02-06 Updated TERM transmembrane receptor protein serine/threonine kinase
2001-04-03 Updated TERM transmembrane receptor protein serine/threonine kinase
2001-03-30 Added XREF EC:2.7.1.-
2001-03-30 Added TERM transmembrane receptor protein serine/threonine kinase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM transmembrane receptor protein serine/threonine kinase activity
2002-02-06 Updated TERM transmembrane receptor protein serine/threonine kinase
2001-04-03 Updated TERM transmembrane receptor protein serine/threonine kinase
2001-03-30 Added TERM transmembrane receptor protein serine/threonine kinase

Definition/synonyms

Timestamp Action Category Detail
2011-01-30 Deleted DEFINITION Catalysis of the reaction: ATP + transmembrane receptor protein serine = ADP + transmembrane receptor protein serine phosphate, and ATP + transmembrane receptor protein threonine = ADP + transmembrane receptor protein threonine phosphate.
2011-01-30 Added DEFINITION Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2010-09-24 Added DEFINITION Catalysis of the reaction: ATP + transmembrane receptor protein serine = ADP + transmembrane receptor protein serine phosphate, and ATP + transmembrane receptor protein threonine = ADP + transmembrane receptor protein threonine phosphate.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.
2007-11-08 Added SYNONYM ATP:receptor-protein phosphotransferase activity
2007-11-08 Added SYNONYM STK13
2007-11-08 Added SYNONYM TGF-beta kinase activity
2007-11-08 Added SYNONYM activin receptor kinase activity
2007-11-08 Added SYNONYM receptor protein serine/threonine kinase activity
2007-11-08 Added SYNONYM receptor serine/threonine protein kinase activity
2007-11-08 Added SYNONYM receptor type I serine/threonine protein kinase activity
2007-11-08 Added SYNONYM receptor type II serine/threonine protein kinase activity
2007-10-25 Added DEFINITION Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate.

Relationships

Timestamp Action Category Detail
2012-02-18 Added RELATION part of GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway)
2011-02-15 Added RELATION is a GO:0004674 (protein serine/threonine kinase activity)
2010-11-04 Deleted RELATION is a GO:0004702 (receptor signaling protein serine/threonine kinase activity)
2008-04-01 Updated RELATION is a GO:0019199 (transmembrane receptor protein kinase activity)
2008-04-01 Updated RELATION is a GO:0004702 (receptor signaling protein serine/threonine kinase activity)

Cross-references

Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:2.7.11.30-RXN
2007-09-26 Added XREF EC:2.7.11.-
2007-09-26 Deleted XREF EC:2.7.1.-
2001-03-30 Added XREF EC:2.7.1.-
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
18ms