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GO:0004667 prostaglandin-D synthase activity

Term Information

ID GO:0004667
Name prostaglandin-D synthase activity
Ontology Molecular Function
Definition Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
GONUTS GO:0004667 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact PGD2 synthase activity
exact prostaglandin-H2 D-isomerase activity
exact prostaglandin-R-prostaglandin D isomerase activity
exact (5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity
exact PGH-PGD isomerase activity
exact prostaglandin D2 synthase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 5.3.99.2
KEGG R02266
MetaCyc PROSTAGLANDIN-D-SYNTHASE-RXN
RHEA 10603

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004667:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004667. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004667 based on the entire annotation set Co-occurrence statistics for GO:0004667 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2010-10-11 Added XREF RHEA:10603
2010-10-11 Added XREF KEGG:R02266
2008-05-13 Added DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2008-04-01 Updated RELATION is a GO:0016860 (intramolecular oxidoreductase activity)
2007-11-08 Added SYNONYM (5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity
2007-11-08 Added SYNONYM prostaglandin-R-prostaglandin D isomerase activity
2007-09-06 Added SYNONYM PGD2 synthase activity
2007-09-06 Added SYNONYM PGH-PGD isomerase activity
2007-09-06 Added SYNONYM prostaglandin D2 synthase activity
2007-09-06 Added SYNONYM prostaglandin-H2 D-isomerase activity
2003-10-27 Added XREF MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN
2003-03-19 Updated TERM prostaglandin-D synthase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2002-02-06 Updated TERM prostaglandin-D synthase
2001-04-03 Updated TERM prostaglandin-D synthase
2001-03-30 Added XREF EC:5.3.99.2
2001-03-30 Added TERM prostaglandin-D synthase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM prostaglandin-D synthase activity
2002-02-06 Updated TERM prostaglandin-D synthase
2001-04-03 Updated TERM prostaglandin-D synthase
2001-03-30 Added TERM prostaglandin-D synthase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2008-05-13 Added DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2007-11-08 Added SYNONYM (5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity
2007-11-08 Added SYNONYM prostaglandin-R-prostaglandin D isomerase activity
2007-09-06 Added SYNONYM PGD2 synthase activity
2007-09-06 Added SYNONYM PGH-PGD isomerase activity
2007-09-06 Added SYNONYM prostaglandin D2 synthase activity
2007-09-06 Added SYNONYM prostaglandin-H2 D-isomerase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016860 (intramolecular oxidoreductase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:10603
2010-10-11 Added XREF KEGG:R02266
2003-10-27 Added XREF MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN
2001-03-30 Added XREF EC:5.3.99.2
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