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GO:0004656 procollagen-proline 4-dioxygenase activity

Term Information

ID GO:0004656
Name procollagen-proline 4-dioxygenase activity
Ontology Molecular Function
Definition Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
GONUTS GO:0004656 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact protocollagen prolyl hydroxylase activity
exact protocollagen proline hydroxylase activity
exact protocollagen proline dioxygenase activity
exact protocollagen proline 4-hydroxylase activity
exact prolylprotocollagen hydroxylase activity
exact prolylprotocollagen dioxygenase activity
exact prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity
exact proline protocollagen hydroxylase activity
exact procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity
exact peptidyl proline hydroxylase activity
exact hydroxylase, collagen proline activity
exact collagen proline hydroxylase activity
broad protocollagen hydroxylase activity
broad prolyl hydroxylase activity
broad prolyl 4-hydroxylase activity
broad proline,2-oxoglutarate 4-dioxygenase activity
broad proline hydroxylase activity
exact procollagen-proline,2-oxoglutarate-4-dioxygenase activity
exact proline, 2-oxoglutarate dioxygenase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.14.11.2
InterPro IPR013547
KEGG R03219
MetaCyc 1.14.11.2-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004656:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004656. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004656 based on the entire annotation set Co-occurrence statistics for GO:0004656 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-03 Added XREF KEGG:R03219
2008-05-13 Added DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
2008-04-01 Updated RELATION is a GO:0019798 (procollagen-proline dioxygenase activity)
2008-04-01 Updated RELATION is a GO:0031545 (peptidyl-proline 4-dioxygenase activity)
2007-12-14 Added SYNONYM collagen proline hydroxylase activity
2007-12-14 Added SYNONYM hydroxylase, collagen proline activity
2007-12-14 Added SYNONYM peptidyl proline hydroxylase activity
2007-12-14 Added SYNONYM procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity
2007-12-14 Added SYNONYM proline protocollagen hydroxylase activity
2007-12-14 Added SYNONYM proline, 2-oxoglutarate dioxygenase activity
2007-12-14 Added SYNONYM prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity
2007-12-14 Added SYNONYM prolylprotocollagen dioxygenase activity
2007-12-14 Added SYNONYM prolylprotocollagen hydroxylase activity
2007-12-14 Added SYNONYM protocollagen proline 4-hydroxylase activity
2007-12-14 Added SYNONYM protocollagen proline dioxygenase activity
2007-12-14 Added SYNONYM protocollagen proline hydroxylase activity
2007-12-14 Added SYNONYM protocollagen prolyl hydroxylase activity
2007-10-16 Deleted SYNONYM procollagen-proline 4-dioxygenase activity
2007-09-06 Added SYNONYM procollagen-proline 4-dioxygenase activity
2007-09-06 Added SYNONYM proline hydroxylase activity
2007-09-06 Added SYNONYM proline,2-oxoglutarate 4-dioxygenase activity
2007-09-06 Added SYNONYM prolyl 4-hydroxylase activity
2007-09-06 Added SYNONYM prolyl hydroxylase activity
2007-09-06 Added SYNONYM protocollagen hydroxylase activity
2007-09-06 Deleted SYNONYM prolyl 4-hydroxylase
2007-08-09 Added SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2007-08-09 Added SYNONYM prolyl 4-hydroxylase
2007-08-09 Deleted SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2007-08-09 Deleted SYNONYM prolyl 4-hydroxylase
2006-01-07 Deleted SYNONYM procollagen-proline dioxygenase activity
2004-04-19 Added SYNONYM procollagen-proline dioxygenase activity
2004-04-19 Added SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2004-04-19 Added SYNONYM prolyl 4-hydroxylase
2004-04-16 Deleted SYNONYM procollagen-proline dioxygenase activity
2004-04-16 Deleted SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2004-04-16 Deleted SYNONYM prolyl 4-hydroxylase
2004-02-21 Added SYNONYM prolyl 4-hydroxylase
2003-10-27 Added SYNONYM procollagen-proline dioxygenase activity
2003-10-27 Added SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2003-10-27 Added XREF MetaCyc:1.14.11.2-RXN
2003-10-23 Updated DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
2003-09-09 Updated TERM procollagen-proline 4-dioxygenase activity
2003-03-19 Updated TERM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + carbon dioxide.
2002-02-06 Updated TERM procollagen-proline,2-oxoglutarate-4-dioxygenase
2001-04-03 Updated TERM procollagen-proline,2-oxoglutarate-4-dioxygenase
2001-03-30 Added XREF EC:1.14.11.2
2001-03-30 Added TERM procollagen-proline,2-oxoglutarate-4-dioxygenase

Term

Timestamp Action Category Detail
2003-09-09 Updated TERM procollagen-proline 4-dioxygenase activity
2003-03-19 Updated TERM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2002-02-06 Updated TERM procollagen-proline,2-oxoglutarate-4-dioxygenase
2001-04-03 Updated TERM procollagen-proline,2-oxoglutarate-4-dioxygenase
2001-03-30 Added TERM procollagen-proline,2-oxoglutarate-4-dioxygenase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
2007-12-14 Added SYNONYM collagen proline hydroxylase activity
2007-12-14 Added SYNONYM hydroxylase, collagen proline activity
2007-12-14 Added SYNONYM peptidyl proline hydroxylase activity
2007-12-14 Added SYNONYM procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity
2007-12-14 Added SYNONYM proline protocollagen hydroxylase activity
2007-12-14 Added SYNONYM proline, 2-oxoglutarate dioxygenase activity
2007-12-14 Added SYNONYM prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity
2007-12-14 Added SYNONYM prolylprotocollagen dioxygenase activity
2007-12-14 Added SYNONYM prolylprotocollagen hydroxylase activity
2007-12-14 Added SYNONYM protocollagen proline 4-hydroxylase activity
2007-12-14 Added SYNONYM protocollagen proline dioxygenase activity
2007-12-14 Added SYNONYM protocollagen proline hydroxylase activity
2007-12-14 Added SYNONYM protocollagen prolyl hydroxylase activity
2007-10-16 Deleted SYNONYM procollagen-proline 4-dioxygenase activity
2007-09-06 Added SYNONYM procollagen-proline 4-dioxygenase activity
2007-09-06 Added SYNONYM proline hydroxylase activity
2007-09-06 Added SYNONYM proline,2-oxoglutarate 4-dioxygenase activity
2007-09-06 Added SYNONYM prolyl 4-hydroxylase activity
2007-09-06 Added SYNONYM prolyl hydroxylase activity
2007-09-06 Added SYNONYM protocollagen hydroxylase activity
2007-09-06 Deleted SYNONYM prolyl 4-hydroxylase
2007-08-09 Added SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2007-08-09 Added SYNONYM prolyl 4-hydroxylase
2007-08-09 Deleted SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2007-08-09 Deleted SYNONYM prolyl 4-hydroxylase
2006-01-07 Deleted SYNONYM procollagen-proline dioxygenase activity
2004-04-19 Added SYNONYM procollagen-proline dioxygenase activity
2004-04-19 Added SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2004-04-19 Added SYNONYM prolyl 4-hydroxylase
2004-04-16 Deleted SYNONYM procollagen-proline dioxygenase activity
2004-04-16 Deleted SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2004-04-16 Deleted SYNONYM prolyl 4-hydroxylase
2004-02-21 Added SYNONYM prolyl 4-hydroxylase
2003-10-27 Added SYNONYM procollagen-proline dioxygenase activity
2003-10-27 Added SYNONYM procollagen-proline,2-oxoglutarate-4-dioxygenase activity
2003-10-23 Updated DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
2002-11-27 Added DEFINITION Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + carbon dioxide.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0019798 (procollagen-proline dioxygenase activity)
2008-04-01 Updated RELATION is a GO:0031545 (peptidyl-proline 4-dioxygenase activity)

Cross-references

Timestamp Action Category Detail
2010-09-03 Added XREF KEGG:R03219
2003-10-27 Added XREF MetaCyc:1.14.11.2-RXN
2001-03-30 Added XREF EC:1.14.11.2
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