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GO:0004655 porphobilinogen synthase activity

Term Information

ID GO:0004655
Name porphobilinogen synthase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen.
GONUTS GO:0004655 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact delta-aminolevulinic acid dehydrase activity
exact delta-aminolevulinic dehydratase activity
exact delta-aminolevulinate dehydratase activity
exact delta-aminolevulinic acid dehydratase activity
exact aminolevulinic dehydratase activity
exact 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)
exact 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)
exact 5-levulinic acid dehydratase activity
exact aminolevulinate dehydratase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 4.2.1.24
InterPro IPR001731
KEGG R00036
MetaCyc PORPHOBILSYNTH-RXN
RHEA 24067

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004655:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004655. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004655 based on the entire annotation set Co-occurrence statistics for GO:0004655 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen.
2010-10-11 Added XREF KEGG:R00036
2010-10-11 Added XREF RHEA:24067
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.
2008-04-01 Updated RELATION is a GO:0016836 (hydro-lyase activity)
2007-11-08 Added SYNONYM 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)
2007-11-08 Added SYNONYM 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)
2007-11-08 Added SYNONYM 5-levulinic acid dehydratase activity
2007-11-08 Added SYNONYM aminolevulinic dehydratase activity
2007-11-08 Added SYNONYM delta-aminolevulinate dehydratase activity
2007-11-08 Added SYNONYM delta-aminolevulinic acid dehydrase activity
2007-11-08 Added SYNONYM delta-aminolevulinic dehydratase activity
2007-08-09 Added SYNONYM aminolevulinate dehydratase activity
2007-08-09 Added SYNONYM delta-aminolevulinic acid dehydratase activity
2007-08-09 Deleted SYNONYM aminolevulinate dehydratase activity
2007-08-09 Deleted SYNONYM delta-aminolevulinic acid dehydratase activity
2004-07-08 Added SYNONYM aminolevulinate dehydratase activity
2004-07-08 Added SYNONYM delta-aminolevulinic acid dehydratase activity
2004-07-04 Deleted SYNONYM aminolevulinate dehydratase activity
2004-07-04 Deleted SYNONYM delta-aminolevulinic acid dehydratase activity
2004-06-24 Added SYNONYM aminolevulinate dehydratase activity
2004-06-24 Added SYNONYM delta-aminolevulinic acid dehydratase activity
2003-10-27 Added XREF MetaCyc:PORPHOBILSYNTH-RXN
2003-03-19 Updated TERM porphobilinogen synthase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.
2002-02-06 Updated TERM porphobilinogen synthase
2001-04-03 Updated TERM porphobilinogen synthase
2001-03-30 Added XREF EC:4.2.1.24
2001-03-30 Added TERM porphobilinogen synthase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM porphobilinogen synthase activity
2002-02-06 Updated TERM porphobilinogen synthase
2001-04-03 Updated TERM porphobilinogen synthase
2001-03-30 Added TERM porphobilinogen synthase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.
2007-11-08 Added SYNONYM 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)
2007-11-08 Added SYNONYM 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)
2007-11-08 Added SYNONYM 5-levulinic acid dehydratase activity
2007-11-08 Added SYNONYM aminolevulinic dehydratase activity
2007-11-08 Added SYNONYM delta-aminolevulinate dehydratase activity
2007-11-08 Added SYNONYM delta-aminolevulinic acid dehydrase activity
2007-11-08 Added SYNONYM delta-aminolevulinic dehydratase activity
2007-08-09 Added SYNONYM aminolevulinate dehydratase activity
2007-08-09 Added SYNONYM delta-aminolevulinic acid dehydratase activity
2007-08-09 Deleted SYNONYM aminolevulinate dehydratase activity
2007-08-09 Deleted SYNONYM delta-aminolevulinic acid dehydratase activity
2004-07-08 Added SYNONYM aminolevulinate dehydratase activity
2004-07-08 Added SYNONYM delta-aminolevulinic acid dehydratase activity
2004-07-04 Deleted SYNONYM aminolevulinate dehydratase activity
2004-07-04 Deleted SYNONYM delta-aminolevulinic acid dehydratase activity
2004-06-24 Added SYNONYM aminolevulinate dehydratase activity
2004-06-24 Added SYNONYM delta-aminolevulinic acid dehydratase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016836 (hydro-lyase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF KEGG:R00036
2010-10-11 Added XREF RHEA:24067
2003-10-27 Added XREF MetaCyc:PORPHOBILSYNTH-RXN
2001-03-30 Added XREF EC:4.2.1.24
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