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GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity

Term Information

ID GO:0004653
Name polypeptide N-acetylgalactosaminyltransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
GONUTS GO:0004653 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity
exact UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity
exact UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity
exact UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity
exact UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity
exact protein-UDP acetylgalactosaminyltransferase activity
exact uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
exact polypeptide-N-acetylgalactosamine transferase activity
exact glycoprotein acetylgalactosaminyltransferase activity
exact UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity
exact UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
exact UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity
exact UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity
exact UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity
exact UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.4.1.41
MetaCyc 2.4.1.41-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004653:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004653. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004653 based on the entire annotation set Co-occurrence statistics for GO:0004653 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-03 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2010-09-03 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2008-05-13 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2008-04-01 Updated RELATION is a GO:0008376 (acetylgalactosaminyltransferase activity)
2007-11-08 Added SYNONYM UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity
2007-11-08 Added SYNONYM UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity
2007-11-08 Added SYNONYM UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity
2007-11-08 Added SYNONYM UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity
2007-11-08 Added SYNONYM glycoprotein acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM polypeptide-N-acetylgalactosamine transferase activity
2007-11-08 Added SYNONYM uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
2007-09-06 Added SYNONYM protein-UDP acetylgalactosaminyltransferase activity
2003-10-27 Added XREF MetaCyc:2.4.1.41-RXN
2003-03-19 Updated TERM polypeptide N-acetylgalactosaminyltransferase activity
2002-11-27 Updated DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2002-02-06 Updated TERM polypeptide N-acetylgalactosaminyltransferase
2001-08-06 Added DEFINITION An enzyme that modifies serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid. Catalyses the first step in O-glycan biosynthesis.
2001-04-03 Updated TERM polypeptide N-acetylgalactosaminyltransferase
2001-03-30 Added XREF EC:2.4.1.41
2001-03-30 Added TERM polypeptide N-acetylgalactosaminyltransferase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM polypeptide N-acetylgalactosaminyltransferase activity
2002-02-06 Updated TERM polypeptide N-acetylgalactosaminyltransferase
2001-04-03 Updated TERM polypeptide N-acetylgalactosaminyltransferase
2001-03-30 Added TERM polypeptide N-acetylgalactosaminyltransferase

Definition/synonyms

Timestamp Action Category Detail
2010-09-03 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2010-09-03 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2008-05-13 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2007-11-08 Added SYNONYM UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity
2007-11-08 Added SYNONYM UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity
2007-11-08 Added SYNONYM UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity
2007-11-08 Added SYNONYM UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity
2007-11-08 Added SYNONYM glycoprotein acetylgalactosaminyltransferase activity
2007-11-08 Added SYNONYM polypeptide-N-acetylgalactosamine transferase activity
2007-11-08 Added SYNONYM uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
2007-09-06 Added SYNONYM protein-UDP acetylgalactosaminyltransferase activity
2002-11-27 Updated DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
2001-08-06 Added DEFINITION An enzyme that modifies serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid. Catalyses the first step in O-glycan biosynthesis.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008376 (acetylgalactosaminyltransferase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:2.4.1.41-RXN
2001-03-30 Added XREF EC:2.4.1.41
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