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GO:0004653 polypeptide N-acetylgalactosaminyltransferase activityCatalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
Term Information
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| Type | Synonym |
| exact | protein-UDP acetylgalactosaminyltransferase activity |
| exact | UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity |
| exact | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity |
| exact | UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity |
| exact | UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity |
| exact | glycoprotein acetylgalactosaminyltransferase activity |
| exact | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity |
| exact | UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity |
| exact | UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity |
| exact | UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity |
| exact | UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity |
| exact | UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity |
| exact | UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity |
| exact | polypeptide-N-acetylgalactosamine transferase activity |
| exact | uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity |
| Database | ID |
| MetaCyc | 2.4.1.41-RXN |
| EC | 2.4.1.41 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016740 transferase activity | |||||
![]() | ![]() | ![]() | GO:0016757 transferase activity, transferring glycosyl groups | ||||
![]() | ![]() | ![]() | ![]() | GO:0008194 UDP-glycosyltransferase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016758 transferase activity, transferring hexosyl groups | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008376 acetylgalactosaminyltransferase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |