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GO:0004629 phospholipase C activity

Term Information

ID GO:0004629
Name phospholipase C activity
Ontology Molecular Function
Definition Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
Secondary IDs GO:0042298
GONUTS GO:0004629 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related lecithinase C activity
related lipophosphodiesterase C
related phosphatidase C

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR001531
InterPro IPR008475
InterPro IPR028387
InterPro IPR028390
InterPro IPR028393
InterPro IPR028395
InterPro IPR028403
MetaCyc PHOSPHOLIPASE-C-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004629:
Relationship To GO:0004629 Child Term Child Term Name
Is a GO:0004435 phosphatidylinositol phospholipase C activity
Is a GO:0050429 calcium-dependent phospholipase C activity
Positively regulates GO:0010863 positive regulation of phospholipase C activity
Is a GO:0034479 phosphatidylglycerol phospholipase C activity
Is a GO:0034480 phosphatidylcholine phospholipase C activity
Regulates GO:1900274 regulation of phospholipase C activity
Negatively regulates GO:1900275 negative regulation of phospholipase C activity
Is a GO:0052712 inositol phosphosphingolipid phospholipase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004629. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004629 based on the entire annotation set Co-occurrence statistics for GO:0004629 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:PHOSPHOLIPASE-C-RXN
2008-05-30 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2008-05-30 Deleted SYNONYM Clostridium oedematiens beta- and gamma-toxins activity
2008-05-30 Deleted SYNONYM Clostridium welchii alpha-toxin activity
2008-05-30 Deleted SYNONYM lecithinase C activity
2008-05-30 Deleted SYNONYM lipophosphodiesterase I activity
2008-05-30 Deleted SYNONYM alpha-toxin
2008-05-30 Deleted SYNONYM heat-labile hemolysin
2008-05-30 Deleted SYNONYM phosphatidylcholine cholinephosphohydrolase activity
2008-05-30 Added SYNONYM lecithinase C activity
2008-05-30 Deleted XREF MetaCyc:PHOSPHOLIPASE-C-RXN
2008-05-30 Deleted XREF EC:3.1.4.3
2008-05-30 Deleted DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2008-05-30 Added DEFINITION Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
2008-05-13 Added DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2008-04-01 Updated RELATION is a GO:0004620 (phospholipase activity)
2008-04-01 Updated RELATION is a GO:0008081 (phosphoric diester hydrolase activity)
2007-12-14 Added SYNONYM alpha-toxin
2007-12-14 Added SYNONYM heat-labile hemolysin
2007-12-14 Added SYNONYM lipophosphodiesterase C
2007-12-14 Added SYNONYM phosphatidase C
2007-12-14 Added SYNONYM phosphatidylcholine cholinephosphohydrolase activity
2007-09-06 Added SYNONYM Clostridium oedematiens beta- and gamma-toxins activity
2007-09-06 Added SYNONYM Clostridium welchii alpha-toxin activity
2007-09-06 Added SYNONYM lecithinase C activity
2007-09-06 Added SYNONYM lipophosphodiesterase I activity
2007-08-09 Added SYNONYM phospholipase C, acting on phosphatidylcholine
2007-08-09 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2004-04-19 Added SYNONYM phospholipase C, acting on phosphatidylcholine
2004-04-16 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2003-10-27 Added SYNONYM phospholipase C, acting on phosphatidylcholine
2003-10-27 Added XREF MetaCyc:PHOSPHOLIPASE-C-RXN
2003-08-21 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2003-03-19 Updated TERM phospholipase C activity
2002-11-27 Added DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2002-10-12 Added SECONDARY GO:0042298 (phospholipase C, acting on phosphatidylcholine)
2002-10-12 Added XREF EC:3.1.4.3
2002-10-12 Deleted XREF EC:1.3.4.-
2002-10-12 Added SYNONYM phospholipase C, acting on phosphatidylcholine
2002-06-07 Added XREF EC:1.3.4.-
2002-06-07 Deleted XREF EC:3.1.4.3
2002-02-06 Updated TERM phospholipase C
2001-04-03 Updated TERM phospholipase C
2001-03-30 Added XREF EC:3.1.4.3
2001-03-30 Added TERM phospholipase C

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM phospholipase C activity
2002-02-06 Updated TERM phospholipase C
2001-04-03 Updated TERM phospholipase C
2001-03-30 Added TERM phospholipase C

Definition/synonyms

Timestamp Action Category Detail
2008-05-30 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2008-05-30 Deleted SYNONYM Clostridium oedematiens beta- and gamma-toxins activity
2008-05-30 Deleted SYNONYM Clostridium welchii alpha-toxin activity
2008-05-30 Deleted SYNONYM lecithinase C activity
2008-05-30 Deleted SYNONYM lipophosphodiesterase I activity
2008-05-30 Deleted SYNONYM alpha-toxin
2008-05-30 Deleted SYNONYM heat-labile hemolysin
2008-05-30 Deleted SYNONYM phosphatidylcholine cholinephosphohydrolase activity
2008-05-30 Added SYNONYM lecithinase C activity
2008-05-30 Deleted DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2008-05-30 Added DEFINITION Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
2008-05-13 Added DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2007-12-14 Added SYNONYM alpha-toxin
2007-12-14 Added SYNONYM heat-labile hemolysin
2007-12-14 Added SYNONYM lipophosphodiesterase C
2007-12-14 Added SYNONYM phosphatidase C
2007-12-14 Added SYNONYM phosphatidylcholine cholinephosphohydrolase activity
2007-09-06 Added SYNONYM Clostridium oedematiens beta- and gamma-toxins activity
2007-09-06 Added SYNONYM Clostridium welchii alpha-toxin activity
2007-09-06 Added SYNONYM lecithinase C activity
2007-09-06 Added SYNONYM lipophosphodiesterase I activity
2007-08-09 Added SYNONYM phospholipase C, acting on phosphatidylcholine
2007-08-09 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2004-04-19 Added SYNONYM phospholipase C, acting on phosphatidylcholine
2004-04-16 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2003-10-27 Added SYNONYM phospholipase C, acting on phosphatidylcholine
2003-08-21 Deleted SYNONYM phospholipase C, acting on phosphatidylcholine
2002-11-27 Added DEFINITION Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate.
2002-10-12 Added SYNONYM phospholipase C, acting on phosphatidylcholine

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004620 (phospholipase activity)
2008-04-01 Updated RELATION is a GO:0008081 (phosphoric diester hydrolase activity)

Cross-references

Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:PHOSPHOLIPASE-C-RXN
2008-05-30 Deleted XREF MetaCyc:PHOSPHOLIPASE-C-RXN
2008-05-30 Deleted XREF EC:3.1.4.3
2003-10-27 Added XREF MetaCyc:PHOSPHOLIPASE-C-RXN
2002-10-12 Added XREF EC:3.1.4.3
2002-10-12 Deleted XREF EC:1.3.4.-
2002-06-07 Added XREF EC:1.3.4.-
2002-06-07 Deleted XREF EC:3.1.4.3
2001-03-30 Added XREF EC:3.1.4.3

Other

Timestamp Action Category Detail
2002-10-12 Added SECONDARY GO:0042298 (phospholipase C, acting on phosphatidylcholine)
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