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GO:0004602 glutathione peroxidase activity

Term Information

ID GO:0004602
Name glutathione peroxidase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.
Secondary IDs GO:0016224
GONUTS GO:0004602 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact GSH peroxidase activity
exact glutathione:hydrogen-peroxide oxidoreductase activity
narrow non-selenium glutathione peroxidase activity
exact selenium-glutathione peroxidase activity
exact reduced glutathione peroxidase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.11.1.9
InterPro IPR000889
InterPro IPR013376
MetaCyc GLUTATHIONE-PEROXIDASE-RXN
RHEA 16836

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004602:
Relationship To GO:0004602 Child Term Child Term Name
Regulates GO:1903282 regulation of glutathione peroxidase activity
Negatively regulates GO:1903283 negative regulation of glutathione peroxidase activity
Positively regulates GO:1903284 positive regulation of glutathione peroxidase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004602. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004602 based on the entire annotation set Co-occurrence statistics for GO:0004602 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:16836
2010-09-03 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2010-09-03 Added DEFINITION Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2008-04-01 Updated RELATION is a GO:0004601 (peroxidase activity)
2007-11-08 Added SYNONYM GSH peroxidase activity
2007-11-08 Added SYNONYM glutathione:hydrogen-peroxide oxidoreductase activity
2007-11-08 Added SYNONYM reduced glutathione peroxidase activity
2007-11-08 Added SYNONYM selenium-glutathione peroxidase activity
2007-08-09 Added SYNONYM non-selenium glutathione peroxidase activity
2007-08-09 Deleted SYNONYM non-selenium glutathione peroxidase activity
2004-11-25 Added SECONDARY GO:0016224 (non-selenium glutathione peroxidase activity)
2004-11-25 Added SYNONYM non-selenium glutathione peroxidase activity
2003-10-27 Added XREF MetaCyc:GLUTATHIONE-PEROXIDASE-RXN
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2003-03-19 Updated TERM glutathione peroxidase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.
2002-02-06 Updated TERM glutathione peroxidase
2001-04-03 Updated TERM glutathione peroxidase
2001-03-30 Added XREF EC:1.11.1.9
2001-03-30 Added TERM glutathione peroxidase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM glutathione peroxidase activity
2002-02-06 Updated TERM glutathione peroxidase
2001-04-03 Updated TERM glutathione peroxidase
2001-03-30 Added TERM glutathione peroxidase

Definition/synonyms

Timestamp Action Category Detail
2010-09-03 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2010-09-03 Added DEFINITION Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2007-11-08 Added SYNONYM GSH peroxidase activity
2007-11-08 Added SYNONYM glutathione:hydrogen-peroxide oxidoreductase activity
2007-11-08 Added SYNONYM reduced glutathione peroxidase activity
2007-11-08 Added SYNONYM selenium-glutathione peroxidase activity
2007-08-09 Added SYNONYM non-selenium glutathione peroxidase activity
2007-08-09 Deleted SYNONYM non-selenium glutathione peroxidase activity
2004-11-25 Added SYNONYM non-selenium glutathione peroxidase activity
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004601 (peroxidase activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:16836
2003-10-27 Added XREF MetaCyc:GLUTATHIONE-PEROXIDASE-RXN
2001-03-30 Added XREF EC:1.11.1.9

Other

Timestamp Action Category Detail
2004-11-25 Added SECONDARY GO:0016224 (non-selenium glutathione peroxidase activity)
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