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GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity

Term Information

ID GO:0004591
Name oxoglutarate dehydrogenase (succinyl-transferring) activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
GONUTS GO:0004591 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact oxoglutarate dehydrogenase (lipoamide) activity
exact 2-ketoglutarate dehydrogenase activity
exact ketoglutaric dehydrogenase activity
exact oxoglutarate decarboxylase activity
exact oxoglutarate dehydrogenase activity
exact 2-oxoglutarate dehydrogenase activity
exact 2-oxoglutarate: lipoate oxidoreductase activity
exact 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity
exact AKGDH activity
exact OGDC activity
exact alpha-ketoglutarate dehydrogenase activity
exact alpha-ketoglutaric acid dehydrogenase activity
exact alpha-ketoglutaric dehydrogenase activity
exact alpha-oxoglutarate dehydrogenase activity
exact 2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.2.4.2
InterPro IPR011603
MetaCyc 2OXOGLUTDECARB-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004591:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004591. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004591 based on the entire annotation set Co-occurrence statistics for GO:0004591 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:RXN0-1146
2009-05-21 Added XREF MetaCyc:2OXOGLUTDECARB-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
2008-04-01 Updated RELATION is a GO:0016624 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor)
2007-11-08 Added SYNONYM 2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)
2007-09-06 Added SYNONYM 2-ketoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM 2-oxoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM 2-oxoglutarate: lipoate oxidoreductase activity
2007-09-06 Added SYNONYM 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity
2007-09-06 Added SYNONYM AKGDH activity
2007-09-06 Added SYNONYM OGDC activity
2007-09-06 Added SYNONYM alpha-ketoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM alpha-ketoglutaric acid dehydrogenase activity
2007-09-06 Added SYNONYM alpha-ketoglutaric dehydrogenase activity
2007-09-06 Added SYNONYM alpha-oxoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM ketoglutaric dehydrogenase activity
2007-09-06 Added SYNONYM oxoglutarate decarboxylase activity
2007-09-06 Added SYNONYM oxoglutarate dehydrogenase activity
2007-08-09 Added SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2007-08-09 Deleted SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2006-01-22 Added XREF MetaCyc:RXN0-1146
2006-01-22 Deleted XREF MetaCyc:OXOSUC-RXN
2004-04-19 Added SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2004-04-16 Deleted SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2004-01-07 Updated TERM oxoglutarate dehydrogenase (succinyl-transferring) activity
2004-01-07 Added SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2003-10-27 Added XREF MetaCyc:OXOSUC-RXN
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
2003-03-19 Updated TERM oxoglutarate dehydrogenase (lipoamide) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + carbon dioxide.
2002-02-06 Updated TERM oxoglutarate dehydrogenase (lipoamide)
2001-04-03 Updated TERM oxoglutarate dehydrogenase (lipoamide)
2001-03-30 Added XREF EC:1.2.4.2
2001-03-30 Added TERM oxoglutarate dehydrogenase (lipoamide)

Term

Timestamp Action Category Detail
2004-01-07 Updated TERM oxoglutarate dehydrogenase (succinyl-transferring) activity
2003-03-19 Updated TERM oxoglutarate dehydrogenase (lipoamide) activity
2002-02-06 Updated TERM oxoglutarate dehydrogenase (lipoamide)
2001-04-03 Updated TERM oxoglutarate dehydrogenase (lipoamide)
2001-03-30 Added TERM oxoglutarate dehydrogenase (lipoamide)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
2007-11-08 Added SYNONYM 2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)
2007-09-06 Added SYNONYM 2-ketoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM 2-oxoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM 2-oxoglutarate: lipoate oxidoreductase activity
2007-09-06 Added SYNONYM 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity
2007-09-06 Added SYNONYM AKGDH activity
2007-09-06 Added SYNONYM OGDC activity
2007-09-06 Added SYNONYM alpha-ketoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM alpha-ketoglutaric acid dehydrogenase activity
2007-09-06 Added SYNONYM alpha-ketoglutaric dehydrogenase activity
2007-09-06 Added SYNONYM alpha-oxoglutarate dehydrogenase activity
2007-09-06 Added SYNONYM ketoglutaric dehydrogenase activity
2007-09-06 Added SYNONYM oxoglutarate decarboxylase activity
2007-09-06 Added SYNONYM oxoglutarate dehydrogenase activity
2007-08-09 Added SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2007-08-09 Deleted SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2004-04-19 Added SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2004-04-16 Deleted SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2004-01-07 Added SYNONYM oxoglutarate dehydrogenase (lipoamide) activity
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
2002-11-27 Added DEFINITION Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + carbon dioxide.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016624 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor)

Cross-references

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:RXN0-1146
2009-05-21 Added XREF MetaCyc:2OXOGLUTDECARB-RXN
2006-01-22 Added XREF MetaCyc:RXN0-1146
2006-01-22 Deleted XREF MetaCyc:OXOSUC-RXN
2003-10-27 Added XREF MetaCyc:OXOSUC-RXN
2001-03-30 Added XREF EC:1.2.4.2
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