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GO:0004540 ribonuclease activity

Term Information

ID GO:0004540
Name ribonuclease activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GONUTS GO:0004540 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR001900
InterPro IPR002730
InterPro IPR002738
InterPro IPR002759
InterPro IPR004025
InterPro IPR004476
InterPro IPR004659
InterPro IPR005987
InterPro IPR010513
InterPro IPR016191
InterPro IPR016848
InterPro IPR021964
InterPro IPR022907
InterPro IPR024440

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004540:
Relationship To GO:0004540 Child Term Child Term Name
Is a GO:0000171 ribonuclease MRP activity
Is a GO:0004521 endoribonuclease activity
Is a GO:0004532 exoribonuclease activity
Negatively regulates GO:0008428 ribonuclease inhibitor activity
Is a GO:0008995 ribonuclease E activity
Is a GO:0008996 ribonuclease G activity
Is a GO:0008997 ribonuclease R activity
Is a GO:0004549 tRNA-specific ribonuclease activity
Is a GO:0046589 ribonuclease T1 activity
Regulates GO:0060700 regulation of ribonuclease activity
Negatively regulates GO:0060701 negative regulation of ribonuclease activity
Is a GO:0032296 double-stranded RNA-specific ribonuclease activity
Is a GO:0034611 oligoribonucleotidase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
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Date
Assigned By
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Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004540. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004540 based on the entire annotation set Co-occurrence statistics for GO:0004540 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-18 Added RELATION part of GO:0090501 (RNA phosphodiester bond hydrolysis)
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
2008-04-01 Updated RELATION is a GO:0004518 (nuclease activity)
2003-03-26 Updated DEFINITION Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
2003-03-19 Updated TERM ribonuclease activity
2002-02-06 Updated TERM ribonuclease
2001-08-06 Added DEFINITION Any of a group of nuclease enzymes that cleave phosphodiester bonds in chains of RNA.
2001-04-03 Updated TERM ribonuclease
2001-03-30 Added TERM ribonuclease

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM ribonuclease activity
2002-02-06 Updated TERM ribonuclease
2001-04-03 Updated TERM ribonuclease
2001-03-30 Added TERM ribonuclease

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
2003-03-26 Updated DEFINITION Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
2001-08-06 Added DEFINITION Any of a group of nuclease enzymes that cleave phosphodiester bonds in chains of RNA.

Relationships

Timestamp Action Category Detail
2013-12-18 Added RELATION part of GO:0090501 (RNA phosphodiester bond hydrolysis)
2008-04-01 Updated RELATION is a GO:0004518 (nuclease activity)
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