spacer

GO:0004536 deoxyribonuclease activity

Term Information

ID GO:0004536
Name deoxyribonuclease activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
Secondary IDs GO:0004537
GONUTS GO:0004536 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow caspase-activated deoxyribonuclease activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR011578
InterPro IPR016202

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004536:
Relationship To GO:0004536 Child Term Child Term Name
Is a GO:0004520 endodeoxyribonuclease activity
Is a GO:0004529 exodeoxyribonuclease activity
Regulates GO:0032070 regulation of deoxyribonuclease activity
Negatively regulates GO:0032076 negative regulation of deoxyribonuclease activity
Positively regulates GO:0032077 positive regulation of deoxyribonuclease activity
Negatively regulates GO:0060703 deoxyribonuclease inhibitor activity
Is a GO:0034610 oligodeoxyribonucleotidase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004536. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004536 based on the entire annotation set Co-occurrence statistics for GO:0004536 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-18 Added RELATION part of GO:0006308 (DNA catabolic process)
2010-10-07 Added SYNONYM caspase-activated deoxyribonuclease activity
2010-10-07 Added SECONDARY GO:0004537 (caspase-activated deoxyribonuclease activity)
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
2008-04-01 Updated RELATION is a GO:0004518 (nuclease activity)
2003-03-19 Updated TERM deoxyribonuclease activity
2002-11-27 Updated DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
2002-02-06 Updated TERM deoxyribonuclease
2001-08-06 Added DEFINITION An enzyme that catalyzes the hydrolysis of ester linkages within deoxyribonucleic acid.
2001-04-03 Updated TERM deoxyribonuclease
2001-03-30 Added TERM deoxyribonuclease

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM deoxyribonuclease activity
2002-02-06 Updated TERM deoxyribonuclease
2001-04-03 Updated TERM deoxyribonuclease
2001-03-30 Added TERM deoxyribonuclease

Definition/synonyms

Timestamp Action Category Detail
2010-10-07 Added SYNONYM caspase-activated deoxyribonuclease activity
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
2002-11-27 Updated DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
2001-08-06 Added DEFINITION An enzyme that catalyzes the hydrolysis of ester linkages within deoxyribonucleic acid.

Relationships

Timestamp Action Category Detail
2013-12-18 Added RELATION part of GO:0006308 (DNA catabolic process)
2008-04-01 Updated RELATION is a GO:0004518 (nuclease activity)

Other

Timestamp Action Category Detail
2010-10-07 Added SECONDARY GO:0004537 (caspase-activated deoxyribonuclease activity)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
11ms