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GO:0004528 phosphodiesterase I activity

Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.

Term Information

ID GO:0004528
Name phosphodiesterase I activity
Ontology Molecular Function
Definition Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
Comment

Synonyms

Type Synonym
exact orthophosphoric diester phosphohydrolase activity
broad phosphodiesterase activity
exact 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity
related 5'-NPDase activity
related exonuclease I activity
related 5'-phosphodiesterase activity
related 5'-nucleotide phosphodiesterase activity
related 5'-exonuclease activity
related 5'-PDase activity
related 5'NPDE activity
exact PDE I activity
related alkaline phosphodiesterase activity
related 5'-PDE activity
exact oligonucleate 5'-nucleotidohydrolase activity
exact nucleotide pyrophosphatase/phosphodiesterase I activity

Cross-references associated with this term:

Database ID
EC 3.1.4.1
MetaCyc 3.1.4.1-RXN

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Ancestor Chart

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0004518 nuclease activity
GO:0042578 phosphoric ester hydrolase activity
GO:0004527 exonuclease activity
GO:0008081 phosphoric diester hydrolase activity
GO:0004528 phosphodiesterase I activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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