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GO:0004525 ribonuclease III activityCatalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
Term Information
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| Type | Synonym |
| narrow | pre-mRNA 3'-end processing endonuclease |
| exact | ribonuclease 3 activity |
| exact | RNase III activity |
| Database | ID |
| INTERPRO | IPR011907 |
| EC | 3.1.26.3 |
| MetaCyc | 3.1.26.3-RXN |
| INTERPRO | IPR000999 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||||||||
![]() | GO:0003824 catalytic activity | |||||||||
![]() | ![]() | GO:0016787 hydrolase activity | ||||||||
![]() | ![]() | ![]() | GO:0016788 hydrolase activity, acting on ester bonds | |||||||
![]() | ![]() | ![]() | ![]() | GO:0004518 nuclease activity | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0004519 endonuclease activity | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004540 ribonuclease activity | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004521 endoribonuclease activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004525 ribonuclease III activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0016443 bidentate ribonuclease III activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |