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GO:0004520 endodeoxyribonuclease activity

Term Information

ID GO:0004520
Name endodeoxyribonuclease activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
GONUTS GO:0004520 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related endonuclease G activity
related DNA nicking activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR002176
InterPro IPR016644

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0019000 endonuclease G activity CONSIDER GO:0004520

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004520:
Relationship To GO:0004520 Child Term Child Term Name
Is a GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
Is a GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters
Is a GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base
Is a GO:0048256 flap endonuclease activity
Is a GO:0000014 single-stranded DNA endodeoxyribonuclease activity
Is a GO:0009381 excinuclease ABC activity
Is a GO:0015666 restriction endodeoxyribonuclease activity
Regulates GO:0032071 regulation of endodeoxyribonuclease activity
Negatively regulates GO:0032078 negative regulation of endodeoxyribonuclease activity
Positively regulates GO:0032079 positive regulation of endodeoxyribonuclease activity
Is a GO:1990238 double-stranded DNA endodeoxyribonuclease activity
Is a GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity
Is a GO:0000704 pyrimidine dimer DNA N-glycosylase activity
Is a GO:0044824 retroviral 3' processing activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004520. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004520 based on the entire annotation set Co-occurrence statistics for GO:0004520 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-18 Added RELATION part of GO:0000737 (DNA catabolic process, endonucleolytic)
2011-04-10 Added SYNONYM endonuclease G activity
2011-04-10 Deleted SYNONYM endonuclease G activity
2009-11-24 Added SYNONYM DNA nicking activity
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
2008-04-01 Updated RELATION is a GO:0004536 (deoxyribonuclease activity)
2008-04-01 Updated RELATION is a GO:0004519 (endonuclease activity)
2007-08-09 Added SYNONYM endonuclease G activity
2007-08-09 Deleted SYNONYM endonuclease G activity
2005-08-10 Added SYNONYM endonuclease G activity
2003-03-19 Updated TERM endodeoxyribonuclease activity
2002-11-27 Updated DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
2002-02-06 Updated TERM endodeoxyribonuclease
2001-08-06 Added DEFINITION An enzyme that catalyzes the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
2001-04-03 Updated TERM endodeoxyribonuclease
2001-03-30 Added TERM endodeoxyribonuclease

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM endodeoxyribonuclease activity
2002-02-06 Updated TERM endodeoxyribonuclease
2001-04-03 Updated TERM endodeoxyribonuclease
2001-03-30 Added TERM endodeoxyribonuclease

Definition/synonyms

Timestamp Action Category Detail
2011-04-10 Added SYNONYM endonuclease G activity
2011-04-10 Deleted SYNONYM endonuclease G activity
2009-11-24 Added SYNONYM DNA nicking activity
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
2007-08-09 Added SYNONYM endonuclease G activity
2007-08-09 Deleted SYNONYM endonuclease G activity
2005-08-10 Added SYNONYM endonuclease G activity
2002-11-27 Updated DEFINITION Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
2001-08-06 Added DEFINITION An enzyme that catalyzes the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.

Relationships

Timestamp Action Category Detail
2013-12-18 Added RELATION part of GO:0000737 (DNA catabolic process, endonucleolytic)
2008-04-01 Updated RELATION is a GO:0004536 (deoxyribonuclease activity)
2008-04-01 Updated RELATION is a GO:0004519 (endonuclease activity)
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