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GO:0004519 endonuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

Term Information

ID GO:0004519
Name endonuclease activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
Comment

Cross-references associated with this term:

Database ID
INTERPRO IPR007868
INTERPRO IPR007869
INTERPRO IPR009614
INTERPRO IPR009933
INTERPRO IPR007281
INTERPRO IPR001719
INTERPRO IPR002711
INTERPRO IPR007581
INTERPRO IPR000097
INTERPRO IPR003154
INTERPRO IPR004601
INTERPRO IPR011337
INTERPRO IPR003611
INTERPRO IPR003651
INTERPRO IPR016128
INTERPRO IPR013628
INTERPRO IPR004211
INTERPRO IPR004230
INTERPRO IPR006167
INTERPRO IPR001982
INTERPRO IPR004035
INTERPRO IPR004036
INTERPRO IPR004042
INTERPRO IPR001044
INTERPRO IPR018140
INTERPRO IPR007560
INTERPRO IPR007409
INTERPRO IPR018246
INTERPRO IPR004579
INTERPRO IPR004603
INTERPRO IPR010270
INTERPRO IPR003058
INTERPRO IPR003060
INTERPRO IPR008684
INTERPRO IPR004860

This term can be used instead of these obsolete terms:

GO:0008845 endonuclease VIII activity (consider GO:0004519)
GO:0016541 intein (consider GO:0004519)

Web service: term information

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GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0004518 nuclease activity
GO:0004519 endonuclease activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
I GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
I GO:0004520 endodeoxyribonuclease activity
I GO:0004521 endoribonuclease activity
I GO:0043765 T/G mismatch-specific endonuclease activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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