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GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity

Term Information

ID GO:0004514
Name nicotinate-nucleotide diphosphorylase (carboxylating) activity
Ontology Molecular Function
Definition Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.
GONUTS GO:0004514 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact quinolinate phosphoribosyltransferase (decarboxylating) activity
exact quinolinic acid phosphoribosyltransferase activity
exact quinolinic phosphoribosyltransferase activity
exact nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)
exact nicotinate mononucleotide pyrophosphorylase (carboxylating)
exact QAPRTase activity
exact NAD pyrophosphorylase activity
exact nicotinate-nucleotide pyrophosphorylase (carboxylating) activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.4.2.19
InterPro IPR002638
InterPro IPR004393
KEGG R03348
MetaCyc QUINOPRIBOTRANS-RXN
RHEA 12736

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004514:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004514. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004514 based on the entire annotation set Co-occurrence statistics for GO:0004514 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2010-10-11 Added XREF KEGG:R03348
2010-10-11 Added XREF RHEA:12736
2008-05-13 Added DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2008-04-01 Updated RELATION is a GO:0016763 (transferase activity, transferring pentosyl groups)
2007-11-08 Added SYNONYM NAD pyrophosphorylase activity
2007-11-08 Added SYNONYM QAPRTase activity
2007-11-08 Added SYNONYM nicotinate mononucleotide pyrophosphorylase (carboxylating)
2007-11-08 Added SYNONYM nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)
2007-11-08 Added SYNONYM quinolinic acid phosphoribosyltransferase activity
2007-11-08 Added SYNONYM quinolinic phosphoribosyltransferase activity
2007-09-06 Added SYNONYM quinolinate phosphoribosyltransferase (decarboxylating) activity
2007-08-09 Added SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2007-08-09 Deleted SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2004-04-19 Added SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2004-04-16 Deleted SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2003-10-27 Added SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2003-10-27 Added XREF MetaCyc:QUINOPRIBOTRANS-RXN
2003-10-23 Updated DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2003-09-09 Updated TERM nicotinate-nucleotide diphosphorylase (carboxylating) activity
2003-03-19 Updated TERM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + carbon dioxide = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2002-02-06 Updated TERM nicotinate-nucleotide pyrophosphorylase (carboxylating)
2001-04-03 Updated TERM nicotinate-nucleotide pyrophosphorylase (carboxylating)
2001-03-30 Added XREF EC:2.4.2.19
2001-03-30 Added TERM nicotinate-nucleotide pyrophosphorylase (carboxylating)

Term

Timestamp Action Category Detail
2003-09-09 Updated TERM nicotinate-nucleotide diphosphorylase (carboxylating) activity
2003-03-19 Updated TERM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2002-02-06 Updated TERM nicotinate-nucleotide pyrophosphorylase (carboxylating)
2001-04-03 Updated TERM nicotinate-nucleotide pyrophosphorylase (carboxylating)
2001-03-30 Added TERM nicotinate-nucleotide pyrophosphorylase (carboxylating)

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2008-05-13 Added DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2007-11-08 Added SYNONYM NAD pyrophosphorylase activity
2007-11-08 Added SYNONYM QAPRTase activity
2007-11-08 Added SYNONYM nicotinate mononucleotide pyrophosphorylase (carboxylating)
2007-11-08 Added SYNONYM nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)
2007-11-08 Added SYNONYM quinolinic acid phosphoribosyltransferase activity
2007-11-08 Added SYNONYM quinolinic phosphoribosyltransferase activity
2007-09-06 Added SYNONYM quinolinate phosphoribosyltransferase (decarboxylating) activity
2007-08-09 Added SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2007-08-09 Deleted SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2004-04-19 Added SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2004-04-16 Deleted SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2003-10-27 Added SYNONYM nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
2003-10-23 Updated DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
2002-11-27 Added DEFINITION Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + carbon dioxide = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016763 (transferase activity, transferring pentosyl groups)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF KEGG:R03348
2010-10-11 Added XREF RHEA:12736
2003-10-27 Added XREF MetaCyc:QUINOPRIBOTRANS-RXN
2001-03-30 Added XREF EC:2.4.2.19
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