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GO:0004512 inositol-3-phosphate synthase activityCatalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate; requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
Term Information
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| Type | Synonym |
| exact | 1L-myo-inositol-1-phosphate lyase (isomerizing) |
| exact | glucocycloaldolase activity |
| exact | glucose-6-phosphate inositol monophosphate cycloaldolase activity |
| exact | glucose 6-phosphate cyclase activity |
| exact | inositol 1-phosphate synthetase activity |
| exact | D-glucose 6-phosphate cycloaldolase activity |
| exact | inositol 1-phosphate synthatase activity |
| exact | myo-inositol-1-phosphate synthase activity |
| Database | ID |
| MetaCyc | MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN |
| EC | 5.5.1.4 |
| INTERPRO | IPR002587 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||
![]() | GO:0003824 catalytic activity | |||
![]() | ![]() | GO:0016853 isomerase activity | ||
![]() | ![]() | ![]() | GO:0016872 intramolecular lyase activity | |
![]() | ![]() | ![]() | ![]() | GO:0004512 inositol-3-phosphate synthase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-12-16-04-01-54 |