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GO:0004510 tryptophan 5-monooxygenase activityCatalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
Term Information
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| Type | Synonym |
| exact | L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) |
| exact | tryptophan 5-hydroxylase activity |
| exact | tryptophan hydroxylase activity |
| exact | L-tryptophan hydroxylase activity |
| exact | indoleacetic acid-5-hydroxylase activity |
| Database | ID |
| INTERPRO | IPR005963 |
| MetaCyc | TRYPTOPHAN-5-MONOOXYGENASE-RXN |
| EC | 1.14.16.4 |
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| GO:0003674 molecular_function | ||||||
![]() | GO:0003824 catalytic activity | |||||
![]() | ![]() | GO:0016491 oxidoreductase activity | ||||
![]() | ![]() | ![]() | GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | |||
![]() | ![]() | ![]() | ![]() | GO:0004497 monooxygenase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004510 tryptophan 5-monooxygenase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-22-04-02-35 |