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GO:0004504 peptidylglycine monooxygenase activity

Term Information

ID GO:0004504
Name peptidylglycine monooxygenase activity
Ontology Molecular Function
Definition Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
GONUTS GO:0004504 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact peptidylglycine 2-hydroxylase activity
exact PAM activity
exact peptidyl alpha-amidating enzyme activity
exact peptidylglycine alpha-amidating monooxygenase activity
related PAM-A
related PAM-B
related peptide alpha-amidating enzyme
exact peptide alpha-amide synthase activity
exact peptide-alpha-amide synthetase activity
exact peptidylglycine alpha-hydroxylase activity
exact peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)
exact synthase, peptide alpha-amide

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.14.17.3
InterPro IPR000720
MetaCyc PEPTIDYLGLYCINE-MONOOXYGENASE-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004504:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004504. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004504 based on the entire annotation set Co-occurrence statistics for GO:0004504 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
2008-04-01 Updated RELATION is a GO:0016715 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen)
2007-11-08 Added SYNONYM PAM-A
2007-11-08 Added SYNONYM PAM-B
2007-11-08 Added SYNONYM peptide alpha-amidating enzyme
2007-11-08 Added SYNONYM peptide alpha-amide synthase activity
2007-11-08 Added SYNONYM peptide-alpha-amide synthetase activity
2007-11-08 Added SYNONYM peptidylglycine alpha-hydroxylase activity
2007-11-08 Added SYNONYM peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)
2007-11-08 Added SYNONYM synthase, peptide alpha-amide
2007-09-06 Added SYNONYM PAM activity
2007-09-06 Added SYNONYM peptidyl alpha-amidating enzyme activity
2007-09-06 Added SYNONYM peptidylglycine alpha-amidating monooxygenase activity
2007-08-09 Added SYNONYM peptidylglycine 2-hydroxylase activity
2007-08-09 Deleted SYNONYM peptidylglycine 2-hydroxylase activity
2004-04-19 Added SYNONYM peptidylglycine 2-hydroxylase activity
2003-10-27 Added XREF MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN
2003-09-09 Updated TERM peptidylglycine monooxygenase activity
2003-03-19 Updated TERM peptidyl-glycine monooxygenase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
2002-02-06 Updated TERM peptidyl-glycine monooxygenase
2001-11-07 Updated TERM peptidyl-glycine monooxygenase
2001-04-03 Updated TERM peptidylglycine monooxygenase
2001-03-30 Added XREF EC:1.14.17.3
2001-03-30 Added TERM peptidylglycine monooxygenase

Term

Timestamp Action Category Detail
2003-09-09 Updated TERM peptidylglycine monooxygenase activity
2003-03-19 Updated TERM peptidyl-glycine monooxygenase activity
2002-02-06 Updated TERM peptidyl-glycine monooxygenase
2001-11-07 Updated TERM peptidyl-glycine monooxygenase
2001-04-03 Updated TERM peptidylglycine monooxygenase
2001-03-30 Added TERM peptidylglycine monooxygenase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
2007-11-08 Added SYNONYM PAM-A
2007-11-08 Added SYNONYM PAM-B
2007-11-08 Added SYNONYM peptide alpha-amidating enzyme
2007-11-08 Added SYNONYM peptide alpha-amide synthase activity
2007-11-08 Added SYNONYM peptide-alpha-amide synthetase activity
2007-11-08 Added SYNONYM peptidylglycine alpha-hydroxylase activity
2007-11-08 Added SYNONYM peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)
2007-11-08 Added SYNONYM synthase, peptide alpha-amide
2007-09-06 Added SYNONYM PAM activity
2007-09-06 Added SYNONYM peptidyl alpha-amidating enzyme activity
2007-09-06 Added SYNONYM peptidylglycine alpha-amidating monooxygenase activity
2007-08-09 Added SYNONYM peptidylglycine 2-hydroxylase activity
2007-08-09 Deleted SYNONYM peptidylglycine 2-hydroxylase activity
2004-04-19 Added SYNONYM peptidylglycine 2-hydroxylase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016715 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN
2001-03-30 Added XREF EC:1.14.17.3
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