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GO:0004498 calcidiol 1-monooxygenase activityCatalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
Term Information
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| Type | Synonym |
| exact | 25-hydroxycholecalciferol 1-monooxygenase activity |
| exact | 25-hydroxycholecalciferol-1-hydroxylase activity |
| exact | 25-hydroxyvitamin D-1 alpha hydroxylase activity |
| exact | 25-OHD-1 alpha-hydroxylase activity |
| related | 1-hydroxylase-25-hydroxyvitamin D3 |
| exact | 25-hydroxy D3-1alpha-hydroxylase activity |
| exact | 25-hydroxy vitamin D3 1-alpha-hydroxylase activity |
| exact | 25-hydroxycholecalciferol 1alpha-hydroxylase activity |
| exact | 25-hydroxyvitamin D3 1alpha-hydroxylase activity |
| exact | calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating) |
| exact | 25-hydroxycholecalciferol 1-hydroxylase activity |
| narrow | cytochrome P450 CYP27B |
| Database | ID |
| EC | 1.14.13.13 |
| MetaCyc | CALCIDIOL-1-MONOOXYGENASE-RXN |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||||
![]() | GO:0003824 catalytic activity | |||||
![]() | ![]() | GO:0016491 oxidoreductase activity | ||||
![]() | ![]() | ![]() | GO:0004497 monooxygenase activity | |||
![]() | ![]() | ![]() | ![]() | GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | ||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004498 calcidiol 1-monooxygenase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-12-16-04-01-54 |