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GO:0004467 long-chain-fatty-acid-CoA ligase activityCatalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C12-18.
Term Information
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| Type | Synonym |
| related | long-chain fatty acid activation |
| exact | long-chain fatty acid-CoA ligase activity |
| exact | acyl-CoA synthetase activity |
| broad | acyl-activating enzyme activity |
| exact | fatty acid thiokinase (long-chain) activity |
| exact | lignoceroyl-CoA synthase activity |
| narrow | long-chain acyl-CoA synthetase I |
| narrow | long-chain acyl-CoA synthetase II |
| exact | long-chain acyl-coenzyme A synthetase activity |
| exact | long-chain fatty acyl coenzyme A synthetase activity |
| narrow | oleoyl-CoA synthetase |
| narrow | palmitoyl coenzyme A synthetase |
| narrow | palmitoyl-CoA ligase |
| narrow | palmitoyl-CoA synthase |
| narrow | pristanoyl-CoA synthetase |
| narrow | stearoyl-CoA synthetase |
| related | thiokinase |
| narrow | ACS3 |
| narrow | FAA1 |
| exact | LCFA synthetase activity |
| narrow | arachidonyl-CoA synthetase |
| exact | fatty acid thiokinase (long chain) activity |
| exact | long chain fatty acyl-CoA synthetase activity |
| exact | long-chain acyl CoA synthetase activity |
| exact | long-chain acyl-CoA synthetase activity |
| exact | long-chain-fatty-acyl-CoA synthetase activity |
| Database | ID |
| UM-BBD_enzymeID | e0025 |
| MetaCyc | ACYLCOASYN-RXN |
| MetaCyc | PWY-5143 |
| EC | 6.2.1.3 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016874 ligase activity | |||
![]() | ![]() | ![]() | GO:0016877 ligase activity, forming carbon-sulfur bonds | ||
![]() | ![]() | ![]() | ![]() | GO:0015645 fatty-acid ligase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0004467 long-chain-fatty-acid-CoA ligase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-21-04-03-45 |