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GO:0004467 long-chain-fatty-acid-CoA ligase activity

Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C12-18.

Term Information

ID GO:0004467
Name long-chain-fatty-acid-CoA ligase activity
Ontology Molecular Function
Definition Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C12-18.
Comment

Synonyms

Type Synonym
related long-chain fatty acid activation
exact long-chain fatty acid-CoA ligase activity
exact acyl-CoA synthetase activity
broad acyl-activating enzyme activity
exact fatty acid thiokinase (long-chain) activity
exact lignoceroyl-CoA synthase activity
narrow long-chain acyl-CoA synthetase I
narrow long-chain acyl-CoA synthetase II
exact long-chain acyl-coenzyme A synthetase activity
exact long-chain fatty acyl coenzyme A synthetase activity
narrow oleoyl-CoA synthetase
narrow palmitoyl coenzyme A synthetase
narrow palmitoyl-CoA ligase
narrow palmitoyl-CoA synthase
narrow pristanoyl-CoA synthetase
narrow stearoyl-CoA synthetase
related thiokinase
narrow ACS3
narrow FAA1
exact LCFA synthetase activity
narrow arachidonyl-CoA synthetase
exact fatty acid thiokinase (long chain) activity
exact long chain fatty acyl-CoA synthetase activity
exact long-chain acyl CoA synthetase activity
exact long-chain acyl-CoA synthetase activity
exact long-chain-fatty-acyl-CoA synthetase activity

Cross-references associated with this term:

Database ID
UM-BBD_enzymeID e0025
MetaCyc ACYLCOASYN-RXN
MetaCyc PWY-5143
EC 6.2.1.3

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016877 ligase activity, forming carbon-sulfur bonds
GO:0015645 fatty-acid ligase activity
GO:0004467 long-chain-fatty-acid-CoA ligase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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