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GO:0004460 L-lactate dehydrogenase (cytochrome) activity

Term Information

ID GO:0004460
Name L-lactate dehydrogenase (cytochrome) activity
Ontology Molecular Function
Definition Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
GONUTS GO:0004460 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact L-lactate ferricytochrome c oxidoreductase activity
exact dehydrogenase, lactate (cytochrome)
related cytochrome b2 (flavin-free derivative of flavocytochrome b2)
exact L-lactate cytochrome c reductase activity
exact L-lactate cytochrome c oxidoreductase activity
exact L(+)-lactate:cytochrome c oxidoreductase activity
exact lactic cytochrome c reductase activity
exact lactate dehydrogenase (cytochrome)
related cytochrome b2
related flavocytochrome b2
broad lactic acid dehydrogenase activity
exact (S)-lactate:ferricytochrome-c 2-oxidoreductase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.1.2.3
MetaCyc L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004460:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004460. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004460 based on the entire annotation set Co-occurrence statistics for GO:0004460 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:L-LACTATE-DEHYDROGENASE-(CYTOCHROME)-RXN
2009-05-21 Added XREF MetaCyc:L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
2008-04-01 Updated RELATION is a GO:0004457 (lactate dehydrogenase activity)
2008-04-01 Updated RELATION is a GO:0016898 (oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor)
2007-11-08 Added SYNONYM (S)-lactate:ferricytochrome-c 2-oxidoreductase activity
2007-11-08 Added SYNONYM L(+)-lactate:cytochrome c oxidoreductase activity
2007-11-08 Added SYNONYM L-lactate cytochrome c oxidoreductase activity
2007-11-08 Added SYNONYM L-lactate cytochrome c reductase activity
2007-11-08 Added SYNONYM cytochrome b2 (flavin-free derivative of flavocytochrome b2)
2007-11-08 Added SYNONYM dehydrogenase, lactate (cytochrome)
2007-11-08 Added SYNONYM flavocytochrome b2
2007-11-08 Added SYNONYM lactate dehydrogenase (cytochrome)
2007-11-08 Added SYNONYM lactic cytochrome c reductase activity
2007-09-06 Added SYNONYM L-lactate ferricytochrome c oxidoreductase activity
2007-09-06 Added SYNONYM lactic acid dehydrogenase activity
2007-08-09 Added SYNONYM cytochrome b2
2007-08-09 Deleted SYNONYM cytochrome b2
2004-04-19 Added SYNONYM cytochrome b2
2004-04-05 Deleted SYNONYM cytochrome b2
2003-10-27 Added SYNONYM cytochrome b2
2003-10-27 Added XREF MetaCyc:L-LACTATE-DEHYDROGENASE-(CYTOCHROME)-RXN
2003-08-21 Deleted SYNONYM cytochrome b2
2003-03-19 Updated TERM L-lactate dehydrogenase (cytochrome) activity
2003-03-19 Deleted SYNONYM cytochrome-b2
2002-11-27 Added DEFINITION Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
2002-02-06 Updated TERM L-lactate dehydrogenase (cytochrome)
2002-01-08 Added SYNONYM cytochrome b2
2001-04-03 Updated TERM L-lactate dehydrogenase (cytochrome)
2001-03-30 Added XREF EC:1.1.2.3
2001-03-30 Added SYNONYM cytochrome-b2
2001-03-30 Added TERM L-lactate dehydrogenase (cytochrome)

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM L-lactate dehydrogenase (cytochrome) activity
2002-02-06 Updated TERM L-lactate dehydrogenase (cytochrome)
2001-04-03 Updated TERM L-lactate dehydrogenase (cytochrome)
2001-03-30 Added TERM L-lactate dehydrogenase (cytochrome)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
2007-11-08 Added SYNONYM (S)-lactate:ferricytochrome-c 2-oxidoreductase activity
2007-11-08 Added SYNONYM L(+)-lactate:cytochrome c oxidoreductase activity
2007-11-08 Added SYNONYM L-lactate cytochrome c oxidoreductase activity
2007-11-08 Added SYNONYM L-lactate cytochrome c reductase activity
2007-11-08 Added SYNONYM cytochrome b2 (flavin-free derivative of flavocytochrome b2)
2007-11-08 Added SYNONYM dehydrogenase, lactate (cytochrome)
2007-11-08 Added SYNONYM flavocytochrome b2
2007-11-08 Added SYNONYM lactate dehydrogenase (cytochrome)
2007-11-08 Added SYNONYM lactic cytochrome c reductase activity
2007-09-06 Added SYNONYM L-lactate ferricytochrome c oxidoreductase activity
2007-09-06 Added SYNONYM lactic acid dehydrogenase activity
2007-08-09 Added SYNONYM cytochrome b2
2007-08-09 Deleted SYNONYM cytochrome b2
2004-04-19 Added SYNONYM cytochrome b2
2004-04-05 Deleted SYNONYM cytochrome b2
2003-10-27 Added SYNONYM cytochrome b2
2003-08-21 Deleted SYNONYM cytochrome b2
2003-03-19 Deleted SYNONYM cytochrome-b2
2002-11-27 Added DEFINITION Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
2002-01-08 Added SYNONYM cytochrome b2
2001-03-30 Added SYNONYM cytochrome-b2

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004457 (lactate dehydrogenase activity)
2008-04-01 Updated RELATION is a GO:0016898 (oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor)

Cross-references

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:L-LACTATE-DEHYDROGENASE-(CYTOCHROME)-RXN
2009-05-21 Added XREF MetaCyc:L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN
2003-10-27 Added XREF MetaCyc:L-LACTATE-DEHYDROGENASE-(CYTOCHROME)-RXN
2001-03-30 Added XREF EC:1.1.2.3
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