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GO:0004435 phosphoinositide phospholipase C activityCatalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Term Information
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| Type | Synonym |
| exact | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity |
| related | phosphatidylinositol-4,5-bisphosphate hydrolysis |
| exact | 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity |
| broad | triphosphoinositide phosphodiesterase activity |
| exact | phosphoinositidase C activity |
| exact | phosphatidylinositol phospholipase C activity |
| broad | monophosphatidylinositol phosphodiesterase activity |
| exact | PI-PLC activity |
| exact | 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity |
| Database | ID |
| INTERPRO | IPR016279 |
| INTERPRO | IPR001192 |
| EC | 3.1.4.11 |
| MetaCyc | 3.1.4.11-RXN |
| INTERPRO | IPR009535 |
| INTERPRO | IPR001711 |
| INTERPRO | IPR014815 |
GO:0007203 phosphatidylinositol-4,5-bisphosphate hydrolysis |
(consider GO:0004435) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||||||||
![]() | GO:0003824 catalytic activity | |||||||||
![]() | ![]() | GO:0016787 hydrolase activity | ||||||||
![]() | ![]() | ![]() | GO:0016788 hydrolase activity, acting on ester bonds | |||||||
![]() | ![]() | ![]() | ![]() | GO:0016298 lipase activity | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0042578 phosphoric ester hydrolase activity | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008081 phosphoric diester hydrolase activity | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004620 phospholipase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004629 phospholipase C activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004435 phosphoinositide phospholipase C activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |