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GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activityCatalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+.
Term Information
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| Type | Synonym |
| broad | 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity |
| broad | HMG-CoA reductase activity |
| Database | ID |
| INTERPRO | IPR004816 |
| INTERPRO | IPR004554 |
| INTERPRO | IPR002202 |
| EC | 1.1.1.34 |
| MetaCyc | 1.1.1.34-RXN |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016491 oxidoreductase activity | |||
![]() | ![]() | ![]() | GO:0016614 oxidoreductase activity, acting on CH-OH group of donors | ||
![]() | ![]() | ![]() | ![]() | GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |