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GO:0004410 homocitrate synthase activityCatalysis of the reaction: acetyl-CoA + H2O + 2-oxoglutarate = 2-hydroxybutane-1,2,4-tricarboxylate + CoA.
Term Information
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| Type | Synonym |
| exact | acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity |
| exact | 2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating) |
| exact | acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming) |
| exact | homocitrate synthetase activity |
| exact | 2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity |
| Database | ID |
| MetaCyc | HOMOCITRATE-SYNTHASE-RXN |
| INTERPRO | IPR013477 |
| EC | 2.3.3.14 |
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| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016740 transferase activity | |||
![]() | ![]() | ![]() | GO:0016746 transferase activity, transferring acyl groups | ||
![]() | ![]() | ![]() | ![]() | GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0004410 homocitrate synthase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-12-08-04-03-05 |