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GO:0004386 helicase activity

Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA or RNA helix.

Term Information

ID GO:0004386
Name helicase activity
Ontology Molecular Function
Definition Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA or RNA helix.
Comment Note that most helicases catalyze processive duplex unwinding.

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_candida91
goslim_goa62
goslim_pir470
goslim_yeast93

Cross-references associated with this term:

Database ID
INTERPRO IPR010003
INTERPRO IPR018999
INTERPRO IPR013237
INTERPRO IPR007502
INTERPRO IPR006310
INTERPRO IPR012562
INTERPRO IPR004004
INTERPRO IPR003840
INTERPRO IPR004576
INTERPRO IPR005118
INTERPRO IPR001650

Web service: term information

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GTerm?id=termID&format=format

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016462 pyrophosphatase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0004386 helicase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0003678 DNA helicase activity
I GO:0003724 RNA helicase activity
I GO:0033677 DNA/RNA helicase activity
I GO:0070035 purine NTP-dependent helicase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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