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GO:0004362 glutathione-disulfide reductase activityCatalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.
Term Information
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| Type | Synonym |
| exact | glutathione-disulphide reductase activity |
| exact | NADPH-GSSG reductase activity |
| exact | NADPH-glutathione reductase activity |
| exact | NADPH:oxidized-glutathione oxidoreductase activity |
| exact | glutathione S-reductase activity |
| exact | GSSG reductase activity |
| exact | GSH reductase activity |
| exact | glutathione reductase activity |
| related | oxidized glutathione reduction |
| exact | glutathione reductase (NADPH) activity |
| exact | glutathione:NADP+ oxidoreductase activity |
| Database | ID |
| EC | 1.8.1.7 |
| MetaCyc | GLUTATHIONE-REDUCT-NADPH-RXN |
| INTERPRO | IPR006324 |
| INTERPRO | IPR006322 |
GO:0006128 oxidized glutathione reduction |
(consider GO:0004362) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||||||||
![]() | GO:0016209 antioxidant activity | |||||||||
![]() | ![]() | GO:0003824 catalytic activity | ||||||||
![]() | ![]() | ![]() | GO:0016491 oxidoreductase activity | |||||||
![]() | ![]() | ![]() | ![]() | GO:0016651 oxidoreductase activity, acting on NADH or NADPH | ||||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0016667 oxidoreductase activity, acting on sulfur group of donors | |||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0015036 disulfide oxidoreductase activity | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0015037 peptide disulfide oxidoreductase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0016668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0015038 glutathione disulfide oxidoreductase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004362 glutathione-disulfide reductase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-21-04-03-45 |