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GO:0004354 glutamate dehydrogenase (NADP+) activity

Term Information

ID GO:0004354
Name glutamate dehydrogenase (NADP+) activity
Ontology Molecular Function
Definition Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
GONUTS GO:0004354 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad L-glutamate dehydrogenase
exact L-glutamate:NADP+ oxidoreductase (deaminating)
exact L-glutamic acid dehydrogenase activity
exact NAD(P)-glutamate dehydrogenase activity
exact NAD(P)H-dependent glutamate dehydrogenase activity
exact dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))
broad glutamic acid dehydrogenase
broad glutamic dehydrogenase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.4.1.4
MetaCyc GLUTDEHYD-RXN
MetaCyc GLUTSYNIII-PWY
RHEA 11615

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004354:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004354. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004354 based on the entire annotation set Co-occurrence statistics for GO:0004354 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:11615
2008-05-13 Added DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
2008-04-01 Updated RELATION is a GO:0016639 (oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor)
2007-11-08 Added SYNONYM L-glutamate dehydrogenase
2007-11-08 Added SYNONYM L-glutamate:NADP+ oxidoreductase (deaminating)
2007-11-08 Added SYNONYM L-glutamic acid dehydrogenase activity
2007-11-08 Added SYNONYM NAD(P)-glutamate dehydrogenase activity
2007-11-08 Added SYNONYM NAD(P)H-dependent glutamate dehydrogenase activity
2007-11-08 Added SYNONYM dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))
2007-11-08 Added SYNONYM glutamic acid dehydrogenase
2007-09-06 Added SYNONYM glutamic dehydrogenase activity
2007-07-19 Added XREF MetaCyc:GLUTSYNIII-PWY
2004-01-07 Updated TERM glutamate dehydrogenase (NADP+) activity
2003-10-30 Updated DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
2003-10-27 Added XREF MetaCyc:GLUTDEHYD-RXN
2003-09-06 Updated TERM glutamate dehydrogenase (NADP) activity
2003-03-19 Updated TERM glutamate dehydrogenase (NADP+) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + ammonia + NADPH + H+.
2002-02-06 Updated TERM glutamate dehydrogenase (NADP+)
2001-04-03 Updated TERM glutamate dehydrogenase (NADP+)
2001-03-30 Added XREF EC:1.4.1.4
2001-03-30 Added TERM glutamate dehydrogenase (NADP+)

Term

Timestamp Action Category Detail
2004-01-07 Updated TERM glutamate dehydrogenase (NADP+) activity
2003-09-06 Updated TERM glutamate dehydrogenase (NADP) activity
2003-03-19 Updated TERM glutamate dehydrogenase (NADP+) activity
2002-02-06 Updated TERM glutamate dehydrogenase (NADP+)
2001-04-03 Updated TERM glutamate dehydrogenase (NADP+)
2001-03-30 Added TERM glutamate dehydrogenase (NADP+)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
2007-11-08 Added SYNONYM L-glutamate dehydrogenase
2007-11-08 Added SYNONYM L-glutamate:NADP+ oxidoreductase (deaminating)
2007-11-08 Added SYNONYM L-glutamic acid dehydrogenase activity
2007-11-08 Added SYNONYM NAD(P)-glutamate dehydrogenase activity
2007-11-08 Added SYNONYM NAD(P)H-dependent glutamate dehydrogenase activity
2007-11-08 Added SYNONYM dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))
2007-11-08 Added SYNONYM glutamic acid dehydrogenase
2007-09-06 Added SYNONYM glutamic dehydrogenase activity
2003-10-30 Updated DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
2002-11-27 Added DEFINITION Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + ammonia + NADPH + H+.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016639 (oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:11615
2007-07-19 Added XREF MetaCyc:GLUTSYNIII-PWY
2003-10-27 Added XREF MetaCyc:GLUTDEHYD-RXN
2001-03-30 Added XREF EC:1.4.1.4
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