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GO:0004337 geranyltranstransferase activity

Term Information

ID GO:0004337
Name geranyltranstransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.
Comment Note that this is the second step in the formation of farnesyl diphosphate. The first step is 'dimethylallyltransferase activity ; GO:0004161'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'.
GONUTS GO:0004337 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact farnesyl diphosphate synthetase activity
exact geranyltransferase activity
exact farnesyl pyrophosphate synthetase activity
exact FPP synthetase activity
exact farnesyl-diphosphate synthase activity
exact farnesylpyrophosphate synthetase activity
related geranyl transferase I
exact geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.5.1.10
KEGG R02003
MetaCyc FPPSYN-RXN
RHEA 19364

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004337:
Relationship To GO:0004337 Child Term Child Term Name
Is a GO:0043888 (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity
Is a GO:0016767 geranylgeranyl-diphosphate geranylgeranyltransferase activity

Protein Annotation

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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004337. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004337 based on the entire annotation set Co-occurrence statistics for GO:0004337 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2010-10-11 Added XREF KEGG:R02003
2010-10-11 Added XREF RHEA:19364
2008-05-13 Added DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2008-04-01 Updated RELATION is a GO:0004659 (prenyltransferase activity)
2007-11-08 Added SYNONYM farnesylpyrophosphate synthetase activity
2007-11-08 Added SYNONYM geranyl transferase I
2007-11-08 Added SYNONYM geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity
2007-09-06 Added SYNONYM FPP synthetase activity
2007-09-06 Added SYNONYM farnesyl diphosphate synthetase activity
2007-09-06 Added SYNONYM geranyltransferase activity
2007-09-06 Deleted SYNONYM geranyltransferase
2007-08-09 Added SYNONYM farnesyl pyrophosphate synthetase activity
2007-08-09 Added SYNONYM farnesyl-diphosphate synthase activity
2007-08-09 Added SYNONYM geranyltransferase
2007-08-09 Deleted SYNONYM farnesyl pyrophosphate synthetase activity
2007-08-09 Deleted SYNONYM farnesyl-diphosphate synthase activity
2007-08-09 Deleted SYNONYM geranyltransferase
2004-10-01 Added SYNONYM farnesyl pyrophosphate synthetase activity
2004-10-01 Added SYNONYM farnesyl-diphosphate synthase activity
2004-04-19 Added SYNONYM geranyltransferase
2004-04-16 Deleted SYNONYM geranyltransferase
2003-10-27 Added SYNONYM geranyltransferase
2003-10-27 Added XREF MetaCyc:FPPSYN-RXN
2003-08-21 Deleted SYNONYM geranyltransferase
2003-03-19 Updated TERM geranyltranstransferase activity
2002-11-27 Updated DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2002-02-06 Updated TERM geranyltranstransferase
2001-11-04 Added SYNONYM geranyltransferase
2001-08-06 Added DEFINITION Enzyme that joins a molecule of geranyl diphosphate with a molecule of isopentenyl diphosphate to form trans,trans-farnesyl diphosphate.
2001-04-03 Updated TERM geranyltranstransferase
2001-03-30 Added XREF EC:2.5.1.10
2001-03-30 Added TERM geranyltranstransferase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM geranyltranstransferase activity
2002-02-06 Updated TERM geranyltranstransferase
2001-04-03 Updated TERM geranyltranstransferase
2001-03-30 Added TERM geranyltranstransferase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2008-05-13 Added DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2007-11-08 Added SYNONYM farnesylpyrophosphate synthetase activity
2007-11-08 Added SYNONYM geranyl transferase I
2007-11-08 Added SYNONYM geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity
2007-09-06 Added SYNONYM FPP synthetase activity
2007-09-06 Added SYNONYM farnesyl diphosphate synthetase activity
2007-09-06 Added SYNONYM geranyltransferase activity
2007-09-06 Deleted SYNONYM geranyltransferase
2007-08-09 Added SYNONYM farnesyl pyrophosphate synthetase activity
2007-08-09 Added SYNONYM farnesyl-diphosphate synthase activity
2007-08-09 Added SYNONYM geranyltransferase
2007-08-09 Deleted SYNONYM farnesyl pyrophosphate synthetase activity
2007-08-09 Deleted SYNONYM farnesyl-diphosphate synthase activity
2007-08-09 Deleted SYNONYM geranyltransferase
2004-10-01 Added SYNONYM farnesyl pyrophosphate synthetase activity
2004-10-01 Added SYNONYM farnesyl-diphosphate synthase activity
2004-04-19 Added SYNONYM geranyltransferase
2004-04-16 Deleted SYNONYM geranyltransferase
2003-10-27 Added SYNONYM geranyltransferase
2003-08-21 Deleted SYNONYM geranyltransferase
2002-11-27 Updated DEFINITION Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
2001-11-04 Added SYNONYM geranyltransferase
2001-08-06 Added DEFINITION Enzyme that joins a molecule of geranyl diphosphate with a molecule of isopentenyl diphosphate to form trans,trans-farnesyl diphosphate.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004659 (prenyltransferase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF KEGG:R02003
2010-10-11 Added XREF RHEA:19364
2003-10-27 Added XREF MetaCyc:FPPSYN-RXN
2001-03-30 Added XREF EC:2.5.1.10
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