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GO:0004336 galactosylceramidase activity

Term Information

ID GO:0004336
Name galactosylceramidase activity
Ontology Molecular Function
Definition Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
GONUTS GO:0004336 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact galactosylceramide beta-galactosidase activity
exact galactocerebroside beta-galactosidase activity
exact galactocerebrosidase activity
exact beta-galactosylceramidase activity
exact beta-galactocerebrosidase activity
exact D-galactosyl-N-acylsphingosine galactohydrolase activity
exact lactosylceramidase activity
related lactosylceramidase I
exact galactosylcerebrosidase activity
related galactosylceramidase I
exact galactocerebroside-beta-D-galactosidase activity
exact galactocerebroside galactosidase activity
exact cerebroside galactosidase activity
exact galcerase activity
exact ceramide galactosidase activity
exact cerebroside beta-galactosidase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.2.1.46
InterPro IPR001286
MetaCyc GALACTOSYLCERAMIDASE-RXN
RHEA 14300

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004336:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004336. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004336 based on the entire annotation set Co-occurrence statistics for GO:0004336 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-03-01 Deleted RELATION is a GO:0017040 (ceramidase activity)
2011-10-28 Deleted SYNONYM galactocerebroside.beta-galactosidase activity
2011-10-28 Deleted SYNONYM galactosylceramide.beta-galactosidase activity
2011-09-16 Added XREF RHEA:14300
2008-05-13 Added DEFINITION Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
2008-04-01 Updated RELATION is a GO:0017040 (ceramidase activity)
2008-04-01 Updated RELATION is a GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
2007-11-08 Added SYNONYM D-galactosyl-N-acylsphingosine galactohydrolase activity
2007-11-08 Added SYNONYM beta-galactocerebrosidase activity
2007-11-08 Added SYNONYM beta-galactosylceramidase activity
2007-11-08 Added SYNONYM ceramide galactosidase activity
2007-11-08 Added SYNONYM cerebroside beta-galactosidase activity
2007-11-08 Added SYNONYM cerebroside galactosidase activity
2007-11-08 Added SYNONYM galactocerebroside galactosidase activity
2007-11-08 Added SYNONYM galactocerebroside-beta-D-galactosidase activity
2007-11-08 Added SYNONYM galactocerebroside.beta-galactosidase activity
2007-11-08 Added SYNONYM galactosylceramidase I
2007-11-08 Added SYNONYM galactosylceramide.beta-galactosidase activity
2007-11-08 Added SYNONYM galactosylcerebrosidase activity
2007-11-08 Added SYNONYM lactosylceramidase I
2007-11-08 Added SYNONYM lactosylceramidase activity
2007-09-06 Added SYNONYM galactocerebrosidase activity
2007-09-06 Added SYNONYM galactocerebroside beta-galactosidase activity
2007-09-06 Added SYNONYM galactosylceramide beta-galactosidase activity
2007-09-06 Added SYNONYM galcerase activity
2003-10-27 Added XREF MetaCyc:GALACTOSYLCERAMIDASE-RXN
2003-03-19 Updated TERM galactosylceramidase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
2002-02-06 Updated TERM galactosylceramidase
2001-04-03 Updated TERM galactosylceramidase
2001-03-30 Added XREF EC:3.2.1.46
2001-03-30 Added TERM galactosylceramidase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM galactosylceramidase activity
2002-02-06 Updated TERM galactosylceramidase
2001-04-03 Updated TERM galactosylceramidase
2001-03-30 Added TERM galactosylceramidase

Definition/synonyms

Timestamp Action Category Detail
2011-10-28 Deleted SYNONYM galactocerebroside.beta-galactosidase activity
2011-10-28 Deleted SYNONYM galactosylceramide.beta-galactosidase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
2007-11-08 Added SYNONYM D-galactosyl-N-acylsphingosine galactohydrolase activity
2007-11-08 Added SYNONYM beta-galactocerebrosidase activity
2007-11-08 Added SYNONYM beta-galactosylceramidase activity
2007-11-08 Added SYNONYM ceramide galactosidase activity
2007-11-08 Added SYNONYM cerebroside beta-galactosidase activity
2007-11-08 Added SYNONYM cerebroside galactosidase activity
2007-11-08 Added SYNONYM galactocerebroside galactosidase activity
2007-11-08 Added SYNONYM galactocerebroside-beta-D-galactosidase activity
2007-11-08 Added SYNONYM galactocerebroside.beta-galactosidase activity
2007-11-08 Added SYNONYM galactosylceramidase I
2007-11-08 Added SYNONYM galactosylceramide.beta-galactosidase activity
2007-11-08 Added SYNONYM galactosylcerebrosidase activity
2007-11-08 Added SYNONYM lactosylceramidase I
2007-11-08 Added SYNONYM lactosylceramidase activity
2007-09-06 Added SYNONYM galactocerebrosidase activity
2007-09-06 Added SYNONYM galactocerebroside beta-galactosidase activity
2007-09-06 Added SYNONYM galactosylceramide beta-galactosidase activity
2007-09-06 Added SYNONYM galcerase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.

Relationships

Timestamp Action Category Detail
2012-03-01 Deleted RELATION is a GO:0017040 (ceramidase activity)
2008-04-01 Updated RELATION is a GO:0017040 (ceramidase activity)
2008-04-01 Updated RELATION is a GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:14300
2003-10-27 Added XREF MetaCyc:GALACTOSYLCERAMIDASE-RXN
2001-03-30 Added XREF EC:3.2.1.46
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