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GO:0004312 fatty-acid synthase activityCatalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
Term Information
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| Type | Synonym |
| exact | acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) |
| Database | ID |
| EC | 2.3.1.85 |
| MetaCyc | FATTY-ACID-SYNTHASE-RXN |
| INTERPRO | IPR003965 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||||
![]() | GO:0003824 catalytic activity | |||||
![]() | ![]() | GO:0016740 transferase activity | ||||
![]() | ![]() | ![]() | GO:0016746 transferase activity, transferring acyl groups | |||
![]() | ![]() | ![]() | ![]() | GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups | ||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0008415 acyltransferase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004312 fatty-acid synthase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity |
| I | GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity |
| I | GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| I | GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase activity |
| I | GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity |
| I | GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| I | GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity |
| I | GO:0009922 fatty acid elongase activity |
| I | GO:0016297 acyl-[acyl-carrier-protein] hydrolase activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-12-08-04-03-05 |