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GO:0004310 farnesyl-diphosphate farnesyltransferase activity

Term Information

ID GO:0004310
Name farnesyl-diphosphate farnesyltransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
Comment Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'.
GONUTS GO:0004310 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity
exact presqualene-diphosphate synthase activity
exact presqualene synthase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.5.1.21
InterPro IPR006449
InterPro IPR033904
MetaCyc 2.5.1.21-RXN

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008051 obsolete farnesyl-diphosphate farnesyl transferase complex CONSIDER GO:0004310

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004310:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004310. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004310 based on the entire annotation set Co-occurrence statistics for GO:0004310 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-03 Deleted SYNONYM squalene synthetase activity
2010-09-03 Deleted SYNONYM squalene synthase activity
2010-09-03 Deleted SYNONYM farnesyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
2008-04-01 Deleted SYNONYM farnesyl-diphosphate farnesyltransferase activity
2008-04-01 Updated RELATION is a GO:0004311 (farnesyltranstransferase activity)
2007-11-08 Added SYNONYM farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity
2007-11-08 Added SYNONYM squalene synthase activity
2007-10-01 Added SYNONYM farnesyl-diphosphate farnesyltransferase activity
2007-09-10 Deleted SYNONYM farnesyl-diphosphate farnesyltransferase activity
2007-09-10 Deleted SYNONYM farnesyl-diphosphate farnesyl transferase complex
2007-09-06 Deleted SYNONYM farnesyltransferase
2007-09-06 Deleted SYNONYM squalene synthase
2007-09-06 Added SYNONYM farnesyl-diphosphate farnesyltransferase activity
2007-09-06 Added SYNONYM farnesyltransferase activity
2007-09-06 Added SYNONYM presqualene synthase activity
2007-09-06 Added SYNONYM presqualene-diphosphate synthase activity
2007-09-06 Added SYNONYM squalene synthetase activity
2007-08-09 Added SYNONYM farnesyl-diphosphate farnesyl transferase complex
2007-08-09 Added SYNONYM farnesyltransferase
2007-08-09 Added SYNONYM squalene synthase
2007-08-09 Deleted SYNONYM farnesyl-diphosphate farnesyl transferase complex
2007-08-09 Deleted SYNONYM farnesyltransferase
2007-08-09 Deleted SYNONYM squalene synthase
2005-08-10 Added SYNONYM farnesyl-diphosphate farnesyl transferase complex
2004-04-19 Added SYNONYM squalene synthase
2004-04-16 Deleted SYNONYM squalene synthase
2003-10-27 Added SYNONYM farnesyltransferase
2003-10-27 Added SYNONYM squalene synthase
2003-10-27 Added XREF MetaCyc:2.5.1.21-RXN
2003-08-18 Deleted SYNONYM farnesyltransferase
2003-08-18 Deleted SYNONYM squalene synthase
2003-03-19 Updated TERM farnesyl-diphosphate farnesyltransferase activity
2002-12-17 Added SYNONYM farnesyltransferase
2002-11-27 Updated DEFINITION Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
2002-02-06 Updated TERM farnesyl-diphosphate farnesyltransferase
2001-08-06 Added DEFINITION Enzyme that joins two farnesyl diphosphate molecules to form presqualene diphosphate.
2001-04-03 Updated TERM farnesyl-diphosphate farnesyltransferase
2001-03-30 Added XREF EC:2.5.1.21
2001-03-30 Added SYNONYM squalene synthase
2001-03-30 Added TERM farnesyl-diphosphate farnesyltransferase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM farnesyl-diphosphate farnesyltransferase activity
2002-02-06 Updated TERM farnesyl-diphosphate farnesyltransferase
2001-04-03 Updated TERM farnesyl-diphosphate farnesyltransferase
2001-03-30 Added TERM farnesyl-diphosphate farnesyltransferase

Definition/synonyms

Timestamp Action Category Detail
2010-09-03 Deleted SYNONYM squalene synthetase activity
2010-09-03 Deleted SYNONYM squalene synthase activity
2010-09-03 Deleted SYNONYM farnesyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
2008-04-01 Deleted SYNONYM farnesyl-diphosphate farnesyltransferase activity
2007-11-08 Added SYNONYM farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity
2007-11-08 Added SYNONYM squalene synthase activity
2007-10-01 Added SYNONYM farnesyl-diphosphate farnesyltransferase activity
2007-09-10 Deleted SYNONYM farnesyl-diphosphate farnesyltransferase activity
2007-09-10 Deleted SYNONYM farnesyl-diphosphate farnesyl transferase complex
2007-09-06 Deleted SYNONYM farnesyltransferase
2007-09-06 Deleted SYNONYM squalene synthase
2007-09-06 Added SYNONYM farnesyl-diphosphate farnesyltransferase activity
2007-09-06 Added SYNONYM farnesyltransferase activity
2007-09-06 Added SYNONYM presqualene synthase activity
2007-09-06 Added SYNONYM presqualene-diphosphate synthase activity
2007-09-06 Added SYNONYM squalene synthetase activity
2007-08-09 Added SYNONYM farnesyl-diphosphate farnesyl transferase complex
2007-08-09 Added SYNONYM farnesyltransferase
2007-08-09 Added SYNONYM squalene synthase
2007-08-09 Deleted SYNONYM farnesyl-diphosphate farnesyl transferase complex
2007-08-09 Deleted SYNONYM farnesyltransferase
2007-08-09 Deleted SYNONYM squalene synthase
2005-08-10 Added SYNONYM farnesyl-diphosphate farnesyl transferase complex
2004-04-19 Added SYNONYM squalene synthase
2004-04-16 Deleted SYNONYM squalene synthase
2003-10-27 Added SYNONYM farnesyltransferase
2003-10-27 Added SYNONYM squalene synthase
2003-08-18 Deleted SYNONYM farnesyltransferase
2003-08-18 Deleted SYNONYM squalene synthase
2002-12-17 Added SYNONYM farnesyltransferase
2002-11-27 Updated DEFINITION Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
2001-08-06 Added DEFINITION Enzyme that joins two farnesyl diphosphate molecules to form presqualene diphosphate.
2001-03-30 Added SYNONYM squalene synthase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004311 (farnesyltranstransferase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:2.5.1.21-RXN
2001-03-30 Added XREF EC:2.5.1.21
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