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GO:0004308 exo-alpha-sialidase activity

Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.

Term Information

ID GO:0004308
Name exo-alpha-sialidase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
Comment

Synonyms

Type Synonym
exact N-acylneuraminate glycohydrolase activity
exact neuraminidase activity
exact alpha-neuraminidase activity
exact sialidase activity
exact acetylneuraminyl hydrolase activity
exact acetylneuraminidase activity

Cross-references associated with this term:

Database ID
INTERPRO IPR001860
INTERPRO IPR008377
INTERPRO IPR000665
MetaCyc 3.2.1.18-RXN
EC 3.2.1.18
INTERPRO IPR004124

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Ancestor Chart

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016997 alpha-sialidase activity
GO:0004308 exo-alpha-sialidase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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