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GO:0004298 threonine-type endopeptidase activity

Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.

Term Information

ID GO:0004298
Name threonine-type endopeptidase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
Comment

Synonyms

Type Synonym
narrow large multicatalytic protease
related alkaline protease
related MCP
narrow 26S protease
related ingensin
exact threonine endopeptidase activity
narrow lens neutral proteinase
related multicatalytic endopeptidase complex
narrow multicatalytic proteinase
narrow multicatalytic proteinase (complex)
related prosome
narrow proteasome endopeptidase complex
narrow tricorn protease
narrow tricorn proteinase

Cross-references associated with this term:

Database ID
INTERPRO IPR001353
EC 3.4.25
INTERPRO IPR019982

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0070011 peptidase activity, acting on L-amino acid peptides
GO:0070003 threonine-type peptidase activity
GO:0004175 endopeptidase activity
GO:0004298 threonine-type endopeptidase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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