spacer

GO:0004293 obsolete tissue kallikrein activity

This term is obsolete.
This term was made obsolete because it represents a gene product.

Term Information

ID GO:0004293
Name obsolete tissue kallikrein activity
Ontology Molecular Function
Definition OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
Comment This term was made obsolete because it represents a gene product.
Secondary IDs GO:0004279
GONUTS GO:0004293 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related padreatin
related padutin
related pancreatic kallikrein
related salivary kallikrein
related submandibular kallikrein
related submaxillary kallikrein
related urinary kallikrein
related urokallikrein
related glandular kallikrein activity
related kininogenin activity
exact tissue kallikrein activity
broad bradykininogenase
related callicrein
related depot-padutin
related dilminal D
related glumorin
broad kallidinogenase
related kallikrein
related kidney kallikrein
broad kininogenase
related onokrein P

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Replaced by GO:0004252 Molecular Function serine-type endopeptidase activity

Cross-references

Database ID
EC 3.4.21.35
MetaCyc 3.4.21.35-RXN

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004293:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004293. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004293 based on the entire annotation set Co-occurrence statistics for GO:0004293 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-06-18 Added SYNONYM tissue kallikrein activity
2015-06-18 Updated TERM obsolete tissue kallikrein activity
2010-06-08 Updated TERM tissue kallikrein activity
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-11-08 Added OBSOLETION replaced_by GO:0004252 (serine-type endopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0004252 (serine-type endopeptidase activity)
2008-08-18 Deleted DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2008-08-18 Deleted RELATION is a GO:0004252 (serine-type endopeptidase activity)
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Added OBSOLETION replaced_by GO:0004252 (serine-type endopeptidase activity)
2008-05-13 Added DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2008-05-12 Deleted DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2008-04-01 Updated RELATION is a GO:0004252 (serine-type endopeptidase activity)
2007-11-08 Added SYNONYM bradykininogenase
2007-11-08 Added SYNONYM callicrein
2007-11-08 Added SYNONYM onokrein P
2007-11-08 Added SYNONYM padreatin
2007-11-08 Added SYNONYM padutin
2007-11-08 Added SYNONYM pancreatic kallikrein
2007-11-08 Added SYNONYM salivary kallikrein
2007-11-08 Added SYNONYM submandibular kallikrein
2007-11-08 Added SYNONYM submaxillary kallikrein
2007-11-08 Added SYNONYM urinary kallikrein
2007-11-08 Added SYNONYM urokallikrein
2007-11-08 Added SYNONYM depot-padutin
2007-11-08 Added SYNONYM dilminal D
2007-11-08 Added SYNONYM glumorin
2007-11-08 Added SYNONYM kallidinogenase
2007-11-08 Added SYNONYM kallikrein
2007-11-08 Added SYNONYM kidney kallikrein
2007-11-08 Added SYNONYM kininogenase
2007-09-06 Deleted SYNONYM kininogenase activity
2007-09-06 Added SYNONYM glandular kallikrein activity
2007-09-06 Added SYNONYM kininogenin activity
2007-08-09 Added SYNONYM kininogenase activity
2007-08-09 Deleted SYNONYM kininogenase activity
2004-09-05 Added SYNONYM kininogenase activity
2004-09-05 Added SECONDARY GO:0004279 (kininogenase activity)
2003-10-27 Added XREF MetaCyc:3.4.21.35-RXN
2003-03-19 Updated TERM tissue kallikrein activity
2002-11-27 Added DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2002-02-06 Updated TERM tissue kallikrein
2001-04-03 Updated TERM tissue kallikrein
2001-03-30 Added XREF EC:3.4.21.35
2001-03-30 Added TERM tissue kallikrein

Term

Timestamp Action Category Detail
2015-06-18 Updated TERM obsolete tissue kallikrein activity
2010-06-08 Updated TERM tissue kallikrein activity
2003-03-19 Updated TERM tissue kallikrein activity
2002-02-06 Updated TERM tissue kallikrein
2001-04-03 Updated TERM tissue kallikrein
2001-03-30 Added TERM tissue kallikrein

Obsoletions

Timestamp Action Category Detail
2008-11-08 Added OBSOLETION replaced_by GO:0004252 (serine-type endopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0004252 (serine-type endopeptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0004252 (serine-type endopeptidase activity)

Definition/synonyms

Timestamp Action Category Detail
2015-06-18 Added SYNONYM tissue kallikrein activity
2008-08-18 Deleted DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2008-05-13 Added DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2008-05-12 Deleted DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.
2007-11-08 Added SYNONYM bradykininogenase
2007-11-08 Added SYNONYM callicrein
2007-11-08 Added SYNONYM onokrein P
2007-11-08 Added SYNONYM padreatin
2007-11-08 Added SYNONYM padutin
2007-11-08 Added SYNONYM pancreatic kallikrein
2007-11-08 Added SYNONYM salivary kallikrein
2007-11-08 Added SYNONYM submandibular kallikrein
2007-11-08 Added SYNONYM submaxillary kallikrein
2007-11-08 Added SYNONYM urinary kallikrein
2007-11-08 Added SYNONYM urokallikrein
2007-11-08 Added SYNONYM depot-padutin
2007-11-08 Added SYNONYM dilminal D
2007-11-08 Added SYNONYM glumorin
2007-11-08 Added SYNONYM kallidinogenase
2007-11-08 Added SYNONYM kallikrein
2007-11-08 Added SYNONYM kidney kallikrein
2007-11-08 Added SYNONYM kininogenase
2007-09-06 Deleted SYNONYM kininogenase activity
2007-09-06 Added SYNONYM glandular kallikrein activity
2007-09-06 Added SYNONYM kininogenin activity
2007-08-09 Added SYNONYM kininogenase activity
2007-08-09 Deleted SYNONYM kininogenase activity
2004-09-05 Added SYNONYM kininogenase activity
2002-11-27 Added DEFINITION Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.

Relationships

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Deleted RELATION is a GO:0004252 (serine-type endopeptidase activity)
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-04-01 Updated RELATION is a GO:0004252 (serine-type endopeptidase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3.4.21.35-RXN
2001-03-30 Added XREF EC:3.4.21.35

Other

Timestamp Action Category Detail
2004-09-05 Added SECONDARY GO:0004279 (kininogenase activity)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
15ms