GO:0004222 metalloendopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

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1 Filtering Annotations

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2 Viewing Annotation Statistics

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3 Viewing Annotations

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4 Downloading Annotations

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	9606	Human
	10090	Mouse
	40674	Mammalia
	3398	Magnoliophyta (flowering plants)
	2759	Eukaryota
	1117	Cyanobacteria

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Qualifier:

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colocalizes_with

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NOT

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GO Terms:

GO:0004222

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Annotated from any of these references:

GO_REF:*

GO Reference

GO_REF:0000002

interpro

GO_REF:0000003

enzyme

GO_REF:0000004

spkw

GO_REF:0000019

compara

GO_REF:0000020

hamap

GO_REF:0000023

spsl

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IMP,IGI,IPI,IDA,IEP,EXP

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inferred from mutant phenotype

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inferred from genetic interaction

IPI

inferred from physical interaction

IGC

Inferred from Genomic Context

ISS

inferred from sequence or structural similarity

IDA

inferred from direct assay

IEP

inferred from expression pattern

IEA

inferred from electronic annotation

TAS

traceable author statement

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non-traceable author statement

no data

inferred by curator

RCA

reviewed computational annotation

ISA

inferred from sequence alignment

EXP

inferred from experiment

Annotated with reference:

EC:*

Enzyme Code

EMBL:*

EMBL accession

ENSEMBL:*

Ensembl

HAMAP:*

High-quality Automated and Manual Annotation of microbial Proteomes

InterPro:*

InterPro

IPI:*

International Protein Index

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UniProt Knowledgebase keywords

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SP_SL

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UniProtKB

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Human Proteome Atlas

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LIFEdb

MGI

Mouse Genome Informatics

PINC

Proteome Inc via Locuslink

Reactome

RGD

Rat Genome Database

SGD

Saccharomyces Genome Database

TAIR

The Arabidopsis Information Resource

TIGR

The Institute of Genome Research

UniProtKB

ZFIN

The Zebrafish Information Network

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Web service: annotation

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GAnnotation?format=tsv&limit=max-number-of-rows{&gz}{&q=advanced query}{&field=value{,value}}

Full details can be found on the QuickGO Web Services page.

16ms

Stand-alone

Hostname	tomcat-8.ebi.ac.uk
Uptime	17:46 13/10/2009
Data version	2009-11-20-04-03-08

Terminal

GO:0004222 metalloendopeptidase activity

Term Information

Synonyms

Cross-references associated with this term:

This term can be used instead of these obsolete terms:

Web service: term information

Ancestor Chart

Ancestor Table

Relationship key

Child Terms

Protein Annotation

1 Filtering Annotations

2 Viewing Annotation Statistics

3 Viewing Annotations

4 Downloading Annotations

Web service: annotation

Co-occurring Terms

Co-occurrence statistics