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GO:0004201 caspase-1 activity

This term is obsolete.
This term was made obsolete because it represents a gene product.

Term Information

ID GO:0004201
Name caspase-1 activity
Ontology Molecular Function
Definition OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
Comment This term was made obsolete because it represents a gene product.
GONUTS GO:0004201 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad ICE

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Replaced by GO:0004197 Molecular Function cysteine-type endopeptidase activity

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004201:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004201. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004201 based on the entire annotation set Co-occurrence statistics for GO:0004201 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2010-06-08 Updated TERM caspase-1 activity
2008-08-18 Deleted OBSOLETION replaced_by GO:0030693 (caspase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)
2008-06-03 Added OBSOLETION replaced_by GO:0030693 (caspase activity)
2008-05-13 Added DEFINITION OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2008-05-12 Deleted DEFINITION OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2008-04-01 Updated RELATION is a GO:0008369 (obsolete molecular function)
2007-08-09 Added SYNONYM ICE
2007-08-09 Deleted SYNONYM ICE
2003-11-03 Deleted XREF MetaCyc:3.4.22.36-RXN
2003-11-03 Deleted XREF EC:3.4.22.36
2003-10-27 Added SYNONYM ICE
2003-10-27 Added XREF MetaCyc:3.4.22.36-RXN
2003-08-18 Deleted SYNONYM ICE
2003-05-29 Updated DEFINITION OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2003-03-19 Updated TERM caspase-1 activity
2002-11-27 Updated DEFINITION Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2002-02-06 Updated TERM caspase-1
2001-08-06 Added DEFINITION The release of interleukin 1-beta by specific cleavage of 116-Asp-|-Ala-117 and 27-Asp-|-Gly-28 bonds in precursor. Enzymes with this function can also hydrolyse the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-|-NHMe and are members of the peptidase family C14.
2001-04-03 Updated TERM caspase-1
2001-03-30 Added XREF EC:3.4.22.36
2001-03-30 Added SYNONYM ICE
2001-03-30 Added TERM caspase-1

Term

Timestamp Action Category Detail
2010-06-08 Updated TERM caspase-1 activity
2003-03-19 Updated TERM caspase-1 activity
2002-02-06 Updated TERM caspase-1
2001-04-03 Updated TERM caspase-1
2001-03-30 Added TERM caspase-1

Obsoletions

Timestamp Action Category Detail
2008-08-18 Deleted OBSOLETION replaced_by GO:0030693 (caspase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0004197 (cysteine-type endopeptidase activity)
2008-06-03 Added OBSOLETION replaced_by GO:0030693 (caspase activity)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2008-05-12 Deleted DEFINITION OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2007-08-09 Added SYNONYM ICE
2007-08-09 Deleted SYNONYM ICE
2003-10-27 Added SYNONYM ICE
2003-08-18 Deleted SYNONYM ICE
2003-05-29 Updated DEFINITION OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2002-11-27 Updated DEFINITION Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.
2001-08-06 Added DEFINITION The release of interleukin 1-beta by specific cleavage of 116-Asp-|-Ala-117 and 27-Asp-|-Gly-28 bonds in precursor. Enzymes with this function can also hydrolyse the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-|-NHMe and are members of the peptidase family C14.
2001-03-30 Added SYNONYM ICE

Relationships

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-04-01 Updated RELATION is a GO:0008369 (obsolete molecular function)

Cross-references

Timestamp Action Category Detail
2003-11-03 Deleted XREF MetaCyc:3.4.22.36-RXN
2003-11-03 Deleted XREF EC:3.4.22.36
2003-10-27 Added XREF MetaCyc:3.4.22.36-RXN
2001-03-30 Added XREF EC:3.4.22.36
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