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GO:0004197 cysteine-type endopeptidase activityCatalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
Term Information
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| Type | Synonym |
| exact | thiol endopeptidase activity |
| narrow | lysosomal cysteine-type endopeptidase |
| Database | ID |
| INTERPRO | IPR015471 |
| INTERPRO | IPR001096 |
| INTERPRO | IPR016129 |
| EC | 3.4.22 |
| INTERPRO | IPR008739 |
| INTERPRO | IPR013614 |
| INTERPRO | IPR013193 |
| INTERPRO | IPR012599 |
| INTERPRO | IPR012600 |
| INTERPRO | IPR016510 |
| INTERPRO | IPR000317 |
| INTERPRO | IPR015470 |
| INTERPRO | IPR011600 |
| INTERPRO | IPR001456 |
| INTERPRO | IPR001309 |
| INTERPRO | IPR002138 |
| INTERPRO | IPR002398 |
| INTERPRO | IPR000169 |
| INTERPRO | IPR000199 |
| INTERPRO | IPR004134 |
| INTERPRO | IPR002620 |
| INTERPRO | IPR015469 |
| INTERPRO | IPR000855 |
| INTERPRO | IPR008738 |
| INTERPRO | IPR001665 |
| INTERPRO | IPR002704 |
| INTERPRO | IPR009466 |
| INTERPRO | IPR008741 |
| INTERPRO | IPR008742 |
| INTERPRO | IPR001490 |
| INTERPRO | IPR002868 |
| INTERPRO | IPR002540 |
| INTERPRO | IPR006473 |
| INTERPRO | IPR009669 |
GO:0001509 legumain activity |
(replaced_by GO:0004197) |
GO:0004213 cathepsin B activity |
(replaced_by GO:0004197) |
GO:0010320 arginine/lysine endopeptidase activity |
(replaced_by GO:0004197) |
GO:0004212 lysosomal cysteine-type endopeptidase |
(consider GO:0004197) |
GO:0016946 cathepsin F activity |
(replaced_by GO:0004197) |
GO:0030693 caspase activity |
(replaced_by GO:0004197) |
GO:0031079 picornain 3C activity |
(replaced_by GO:0004197) |
GO:0051404 clostripain activity |
(replaced_by GO:0004197) |
GO:0004200 signaling (initiator) caspase activity |
(replaced_by GO:0004197) |
GO:0004201 caspase-1 activity |
(replaced_by GO:0004197) |
GO:0004202 caspase-2 activity |
(replaced_by GO:0004197) |
GO:0004203 caspase-4 activity |
(replaced_by GO:0004197) |
GO:0004204 caspase-5 activity |
(replaced_by GO:0004197) |
GO:0004205 caspase-8 activity |
(replaced_by GO:0004197) |
GO:0004206 caspase-10 activity |
(replaced_by GO:0004197) |
GO:0004207 effector caspase activity |
(replaced_by GO:0004197) |
GO:0004208 caspase-3 activity |
(replaced_by GO:0004197) |
GO:0004209 caspase-6 activity |
(replaced_by GO:0004197) |
GO:0004210 caspase-7 activity |
(replaced_by GO:0004197) |
GO:0004211 caspase-9 activity |
(replaced_by GO:0004197) |
GO:0004215 cathepsin H activity |
(replaced_by GO:0004197) |
GO:0004216 cathepsin K activity |
(replaced_by GO:0004197) |
GO:0004217 cathepsin L activity |
(replaced_by GO:0004197) |
GO:0004218 cathepsin S activity |
(replaced_by GO:0004197) |
GO:0008129 actinidain activity |
(replaced_by GO:0004197) |
GO:0008423 bleomycin hydrolase activity |
(replaced_by GO:0004197) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016787 hydrolase activity | |||||
![]() | ![]() | ![]() | GO:0008233 peptidase activity | ||||
![]() | ![]() | ![]() | ![]() | GO:0070011 peptidase activity, acting on L-amino acid peptides | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0004175 endopeptidase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008234 cysteine-type peptidase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004197 cysteine-type endopeptidase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0004198 calcium-dependent cysteine-type endopeptidase activity |
| I | GO:0070137 small conjugating protein-specific endopeptidase activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-20-04-03-08 |