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GO:0004190 aspartic-type endopeptidase activityCatalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
Term Information
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| Type | Synonym |
| exact | aspartic endopeptidase activity |
| exact | aspartic protease activity |
| exact | carboxyl protease activity |
| exact | aspartyl protease activity |
| Database | ID |
| INTERPRO | IPR019103 |
| INTERPRO | IPR009119 |
| INTERPRO | IPR009120 |
| EC | 3.4.23 |
| INTERPRO | IPR000696 |
| INTERPRO | IPR001461 |
| INTERPRO | IPR012848 |
| INTERPRO | IPR000250 |
| INTERPRO | IPR001995 |
| INTERPRO | IPR001872 |
| INTERPRO | IPR001641 |
| INTERPRO | IPR000588 |
| INTERPRO | IPR009007 |
| INTERPRO | IPR007369 |
| INTERPRO | IPR000045 |
| INTERPRO | IPR005081 |
| INTERPRO | IPR001969 |
GO:0004191 barrierpepsin activity |
(replaced_by GO:0004190) |
GO:0004192 cathepsin D activity |
(replaced_by GO:0004190) |
GO:0004193 cathepsin E activity |
(replaced_by GO:0004190) |
GO:0004194 pepsin A activity |
(replaced_by GO:0004190) |
GO:0004195 renin activity |
(replaced_by GO:0004190) |
GO:0004196 saccharopepsin activity |
(replaced_by GO:0004190) |
GO:0009005 signal peptidase II activity |
(replaced_by GO:0004190) |
GO:0009049 aspartic-type signal peptidase activity |
(replaced_by GO:0004190) |
GO:0030602 chymosin activity |
(replaced_by GO:0004190) |
GO:0046560 scytalidopepsin B activity |
(replaced_by GO:0004190) |
GO:0046561 penicillopepsin activity |
(replaced_by GO:0004190) |
GO:0008978 prepilin peptidase activity |
(replaced_by GO:0004190) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0016787 hydrolase activity | |||||
![]() | ![]() | ![]() | GO:0008233 peptidase activity | ||||
![]() | ![]() | ![]() | ![]() | GO:0070011 peptidase activity, acting on L-amino acid peptides | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0070001 aspartic-type peptidase activity | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004175 endopeptidase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0004190 aspartic-type endopeptidase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0042500 aspartic endopeptidase activity, intramembrane cleaving |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-20-04-03-08 |