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GO:0004185 serine-type carboxypeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

Term Information

ID GO:0004185
Name serine-type carboxypeptidase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Comment

Synonyms

Type Synonym
exact serine carboxypeptidase activity

Cross-references associated with this term:

Database ID
EC 3.4.16
INTERPRO IPR018202
INTERPRO IPR015567
INTERPRO IPR008442
INTERPRO IPR001563
INTERPRO IPR000667

This term can be used instead of these obsolete terms:

GO:0004187 carboxypeptidase D activity (replaced_by GO:0004185)
GO:0004258 vacuolar carboxypeptidase Y (consider GO:0004185)
GO:0004188 serine-type Pro-X carboxypeptidase activity (replaced_by GO:0004185)
GO:0004186 carboxypeptidase C activity (replaced_by GO:0004185)

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0017171 serine hydrolase activity
GO:0008233 peptidase activity
GO:0070011 peptidase activity, acting on L-amino acid peptides
GO:0008238 exopeptidase activity
GO:0004180 carboxypeptidase activity
GO:0008236 serine-type peptidase activity
GO:0070008 serine-type exopeptidase activity
GO:0004185 serine-type carboxypeptidase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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