spacer
spacer
Type a query for QuickGO...
You can reach the search box using alt+9 (Win/IE), alt+shift+9 (Win/Firefox) or ctrl+9 (Mac)
EBIDatabasesQuickGO

GO:0004181 metallocarboxypeptidase activity

Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Term Information

ID GO:0004181
Name metallocarboxypeptidase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Comment

Cross-references associated with this term:

Database ID
INTERPRO IPR000834
EC 3.4.17
INTERPRO IPR015567
INTERPRO IPR001333

This term can be used instead of these obsolete terms:

GO:0050424 alanine carboxypeptidase activity (replaced_by GO:0004181)
GO:0043275 glutamate carboxypeptidase II activity (replaced_by GO:0004181)
GO:0031368 Pro-X metallocarboxypeptidase activity (replaced_by GO:0004181)
GO:0004189 tubulinyl-Tyr carboxypeptidase activity (replaced_by GO:0004181)
GO:0004184 lysine carboxypeptidase activity (replaced_by GO:0004181)
GO:0004183 carboxypeptidase E activity (replaced_by GO:0004181)
GO:0004182 carboxypeptidase A activity (replaced_by GO:0004181)
GO:0050425 carboxypeptidase B activity (replaced_by GO:0004181)
GO:0004226 Gly-X carboxypeptidase activity (replaced_by GO:0004181)
GO:0008472 metallocarboxypeptidase D activity (replaced_by GO:0004181)

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0070011 peptidase activity, acting on L-amino acid peptides
GO:0008238 exopeptidase activity
GO:0008237 metallopeptidase activity
GO:0004180 carboxypeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0004181 metallocarboxypeptidase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0009046 zinc D-Ala-D-Ala carboxypeptidase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
spacer
11ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-23-04-03-36
Terminal
spacer