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GO:0004177 aminopeptidase activity

Term Information

ID GO:0004177
Name aminopeptidase activity
Ontology Molecular Function
Definition Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
GONUTS GO:0004177 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.4.11
InterPro IPR000787
InterPro IPR000819
InterPro IPR001714
InterPro IPR001948
InterPro IPR002467
InterPro IPR002468
InterPro IPR005944
InterPro IPR007865
InterPro IPR008252
InterPro IPR008283
InterPro IPR008330
InterPro IPR011356
InterPro IPR012778
InterPro IPR012856
InterPro IPR012857
InterPro IPR015570
InterPro IPR015571
InterPro IPR022983
InterPro IPR022984
InterPro IPR023358
InterPro IPR023645
InterPro IPR028595
InterPro IPR029514
UniProtKB-KW Aminopeptidase

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0004178 leucyl aminopeptidase activity REPLACEDBY GO:0004177
GO:0004179 membrane alanyl aminopeptidase activity REPLACEDBY GO:0004177
GO:0004230 glutamyl aminopeptidase activity REPLACEDBY GO:0004177
GO:0004239 methionyl aminopeptidase activity REPLACEDBY GO:0004177
GO:0004250 aminopeptidase I activity REPLACEDBY GO:0004177
GO:0008451 X-Pro aminopeptidase activity REPLACEDBY GO:0004177
GO:0009983 tyrosine aminopeptidase activity REPLACEDBY GO:0004177
GO:0016284 alanine aminopeptidase activity REPLACEDBY GO:0004177
GO:0016285 cytosol alanyl aminopeptidase activity REPLACEDBY GO:0004177
GO:0016804 prolyl aminopeptidase activity REPLACEDBY GO:0004177
GO:0030601 aminopeptidase B activity REPLACEDBY GO:0004177
GO:0042576 aspartyl aminopeptidase activity REPLACEDBY GO:0004177
GO:0051397 N-terminal basic amino acid aminopeptidase activity REPLACEDBY GO:0004177
GO:0051398 N-terminal lysine aminopeptidase activity REPLACEDBY GO:0004177
GO:0051399 N-terminal arginine aminopeptidase activity REPLACEDBY GO:0004177

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004177:
Relationship To GO:0004177 Child Term Child Term Name
Is a GO:0045148 tripeptide aminopeptidase activity
Is a GO:0070005 cysteine-type aminopeptidase activity
Is a GO:0070006 metalloaminopeptidase activity
Is a GO:0070009 serine-type aminopeptidase activity
Is a GO:0008239 dipeptidyl-peptidase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004177. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004177 based on the entire annotation set Co-occurrence statistics for GO:0004177 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-08-18 Deleted DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2008-08-18 Added DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2008-04-01 Updated RELATION is a GO:0008238 (exopeptidase activity)
2006-02-09 Added XREF EC:3.4.11
2006-02-09 Deleted XREF EC:3.4.11.-
2005-06-15 Updated DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2003-03-26 Added DEFINITION Catalysis of the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides.
2003-03-19 Updated TERM aminopeptidase activity
2002-02-06 Updated TERM aminopeptidase
2001-04-03 Updated TERM aminopeptidase
2001-03-30 Added XREF EC:3.4.11.-
2001-03-30 Added TERM aminopeptidase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM aminopeptidase activity
2002-02-06 Updated TERM aminopeptidase
2001-04-03 Updated TERM aminopeptidase
2001-03-30 Added TERM aminopeptidase

Definition/synonyms

Timestamp Action Category Detail
2008-08-18 Deleted DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2008-08-18 Added DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2005-06-15 Updated DEFINITION Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides.
2003-03-26 Added DEFINITION Catalysis of the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008238 (exopeptidase activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:3.4.11
2006-02-09 Deleted XREF EC:3.4.11.-
2001-03-30 Added XREF EC:3.4.11.-
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