spacer

GO:0004152 dihydroorotate dehydrogenase activity

Term Information

ID GO:0004152
Name dihydroorotate dehydrogenase activity
Ontology Molecular Function
Definition Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
GONUTS GO:0004152 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact dihydoorotic acid dehydrogenase activity
exact (S)-dihydroorotate:quinone oxidoreductase activity
exact DHOdehase activity
related (DHO) dehydrogenase activity
narrow dihydroorotate:ubiquinone oxidoreductase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.3.5.2
InterPro IPR001295
InterPro IPR005719
InterPro IPR012135
InterPro IPR024920
KEGG R01868
MetaCyc DIHYDROOROTATE-DEHYDROGENASE-RXN
RHEA 18076

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004152:
Relationship To GO:0004152 Child Term Child Term Name
Is a GO:0004158 dihydroorotate oxidase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004152. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004152 based on the entire annotation set Co-occurrence statistics for GO:0004152 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.
2010-10-11 Added DEFINITION Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
2010-10-11 Added XREF RHEA:18076
2010-09-03 Added RELATION is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor)
2010-09-03 Deleted RELATION is a GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors)
2010-09-03 Added XREF EC:1.3.5.2
2010-09-03 Added XREF KEGG:R01868
2010-09-03 Deleted XREF EC:1.3.99.11
2010-09-03 Added SYNONYM (S)-dihydroorotate:quinone oxidoreductase activity
2010-09-03 Deleted SYNONYM (S)-dihydroorotate:(acceptor) oxidoreductase activity
2010-09-03 Deleted SYNONYM (S)-dihydroorotate:acceptor oxidoreductase activity
2008-06-30 Deleted SYNONYM dihydroorotate:ubiquinone oxidoreductase activity
2008-06-30 Added SYNONYM (DHO) dehydrogenase activity
2008-06-30 Added SYNONYM DHOdehase activity
2008-06-30 Added SYNONYM dihydoorotic acid dehydrogenase activity
2008-06-30 Added SYNONYM dihydroorotate:ubiquinone oxidoreductase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.
2008-04-01 Updated RELATION is a GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors)
2007-11-08 Added SYNONYM (S)-dihydroorotate:(acceptor) oxidoreductase activity
2007-11-08 Added SYNONYM (S)-dihydroorotate:acceptor oxidoreductase activity
2007-11-08 Added SYNONYM dihydroorotate:ubiquinone oxidoreductase activity
2003-10-27 Added XREF MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN
2003-03-19 Updated TERM dihydroorotate dehydrogenase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.
2002-02-06 Updated TERM dihydroorotate dehydrogenase
2001-04-03 Updated TERM dihydroorotate dehydrogenase
2001-03-30 Added XREF EC:1.3.99.11
2001-03-30 Added TERM dihydroorotate dehydrogenase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM dihydroorotate dehydrogenase activity
2002-02-06 Updated TERM dihydroorotate dehydrogenase
2001-04-03 Updated TERM dihydroorotate dehydrogenase
2001-03-30 Added TERM dihydroorotate dehydrogenase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.
2010-10-11 Added DEFINITION Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
2010-09-03 Added SYNONYM (S)-dihydroorotate:quinone oxidoreductase activity
2010-09-03 Deleted SYNONYM (S)-dihydroorotate:(acceptor) oxidoreductase activity
2010-09-03 Deleted SYNONYM (S)-dihydroorotate:acceptor oxidoreductase activity
2008-06-30 Deleted SYNONYM dihydroorotate:ubiquinone oxidoreductase activity
2008-06-30 Added SYNONYM (DHO) dehydrogenase activity
2008-06-30 Added SYNONYM DHOdehase activity
2008-06-30 Added SYNONYM dihydoorotic acid dehydrogenase activity
2008-06-30 Added SYNONYM dihydroorotate:ubiquinone oxidoreductase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.
2007-11-08 Added SYNONYM (S)-dihydroorotate:(acceptor) oxidoreductase activity
2007-11-08 Added SYNONYM (S)-dihydroorotate:acceptor oxidoreductase activity
2007-11-08 Added SYNONYM dihydroorotate:ubiquinone oxidoreductase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor.

Relationships

Timestamp Action Category Detail
2010-09-03 Added RELATION is a GO:0016635 (oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor)
2010-09-03 Deleted RELATION is a GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors)
2008-04-01 Updated RELATION is a GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:18076
2010-09-03 Added XREF EC:1.3.5.2
2010-09-03 Added XREF KEGG:R01868
2010-09-03 Deleted XREF EC:1.3.99.11
2003-10-27 Added XREF MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN
2001-03-30 Added XREF EC:1.3.99.11
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
14ms