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GO:0004148 dihydrolipoyl dehydrogenase activity

Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.

Term Information

ID GO:0004148
Name dihydrolipoyl dehydrogenase activity
Ontology Molecular Function
Definition Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.
Comment

Synonyms

Type Synonym
related E3 component of alpha-ketoacid dehydrogenase complexes activity
related L-protein activity
narrow LDP-Glc activity
narrow LDP-Val activity
exact dehydrolipoate dehydrogenase activity
exact diaphorase activity
exact dihydrolipoic dehydrogenase activity
exact dihydrothioctic dehydrogenase activity
related glycine-cleavage system L-protein activity
exact lipoamide dehydrogenase (NADH) activity
exact lipoamide oxidoreductase (NADH) activity
exact lipoamide reductase (NADH) activity
exact lipoamide reductase activity
exact lipoate dehydrogenase activity
exact lipoic acid dehydrogenase activity
exact lipoyl dehydrogenase activity
exact dihydrolipoamide:NAD+ oxidoreductase
exact protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase
exact protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
exact dihydrolipoamide dehydrogenase activity
related dihydrolipoamide reduction
related dihydrolipoylprotein reduction

Cross-references associated with this term:

Database ID
EC 1.8.1.4
INTERPRO IPR006258
MetaCyc DIHYDLIPOXN-RXN

This term can be used instead of these obsolete terms:

GO:0006132 dihydrolipoylprotein reduction (consider GO:0004148)
GO:0009352 dihydrolipoyl dehydrogenase complex (consider GO:0004148)
GO:0006131 dihydrolipoamide reduction (consider GO:0004148)

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NADH or NADPH
GO:0016667 oxidoreductase activity, acting on sulfur group of donors
GO:0016668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
GO:0004148 dihydrolipoyl dehydrogenase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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