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GO:0004123 cystathionine gamma-lyase activity

Term Information

ID GO:0004123
Name cystathionine gamma-lyase activity
Ontology Molecular Function
Definition Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
Secondary IDs GO:0016225
GONUTS GO:0004123 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)
broad L-cystathionine cysteine-lyase (deaminating)
related homoserine dehydratase activity
related homoserine deaminase activity
broad gamma-cystathionase activity
related homoserine deaminase-cystathionase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 4.4.1.1
KEGG R01001
MetaCyc CYSTAGLY-RXN
RHEA 24918

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004123:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004123. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004123 based on the entire annotation set Co-occurrence statistics for GO:0004123 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Deleted DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2011-09-16 Added DEFINITION Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
2011-09-16 Deleted SYNONYM cystine desulfhydrase activity
2011-09-16 Deleted SYNONYM homoserine deaminase-cystathionase activity
2011-09-16 Deleted SYNONYM gamma-cystathionase activity
2011-09-16 Deleted SYNONYM cystathionase activity
2011-09-16 Deleted SYNONYM cysteine desulfhydrase activity
2011-09-16 Deleted SYNONYM cystathioninase activity
2011-09-16 Added SYNONYM L-cystathionine cysteine-lyase (deaminating)
2011-09-16 Added SYNONYM homoserine dehydratase activity
2011-09-16 Added SYNONYM homoserine deaminase activity
2011-09-16 Added SYNONYM gamma-cystathionase activity
2011-09-16 Added SYNONYM homoserine deaminase-cystathionase activity
2011-09-16 Deleted SYNONYM homoserine dehydratase activity
2011-09-16 Deleted SYNONYM gamma-CTL
2011-09-16 Deleted SYNONYM cystalysin
2011-09-16 Deleted SYNONYM homoserine deaminase activity
2011-09-16 Deleted SYNONYM L-cystathionine cysteine-lyase (deaminating)
2011-09-16 Added XREF RHEA:24918
2011-09-16 Added XREF KEGG:R01001
2008-05-13 Added DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2008-04-01 Updated RELATION is a GO:0016846 (carbon-sulfur lyase activity)
2007-11-08 Added SYNONYM L-cystathionine cysteine-lyase (deaminating)
2007-11-08 Added SYNONYM L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)
2007-11-08 Added SYNONYM cystalysin
2007-11-08 Added SYNONYM gamma-CTL
2007-11-08 Added SYNONYM homoserine deaminase-cystathionase activity
2007-09-06 Added SYNONYM cystathionase activity
2007-09-06 Added SYNONYM cystathioninase activity
2007-09-06 Added SYNONYM cystine desulfhydrase activity
2007-09-06 Added SYNONYM gamma-cystathionase activity
2007-09-06 Added SYNONYM homoserine deaminase activity
2007-09-06 Added SYNONYM homoserine dehydratase activity
2007-08-09 Added SYNONYM cysteine desulfhydrase activity
2007-08-09 Deleted SYNONYM cysteine desulfhydrase activity
2004-12-03 Deleted SYNONYM cysteine desulfurase
2004-12-03 Deleted XREF EC:4.4.1.-
2004-04-19 Added SYNONYM cysteine desulfhydrase activity
2004-04-19 Added SYNONYM cysteine desulfurase
2004-04-16 Deleted SYNONYM cysteine desulfhydrase activity
2004-04-16 Deleted SYNONYM cysteine desulfurase
2004-03-17 Added SYNONYM cysteine desulfhydrase activity
2004-03-17 Added SYNONYM cysteine desulfurase
2004-03-17 Added SECONDARY GO:0016225 (cysteine desulfhydrase activity)
2004-03-17 Added XREF EC:4.4.1.-
2003-10-30 Updated DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2003-10-27 Added XREF MetaCyc:CYSTAGLY-RXN
2003-09-09 Updated TERM cystathionine gamma-lyase activity
2003-03-19 Updated TERM cystathionine-gamma-lyase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + ammonia + 2-oxobutanoate.
2002-02-06 Updated TERM cystathionine-gamma-lyase
2001-04-03 Updated TERM cystathionine-gamma-lyase
2001-03-30 Added XREF EC:4.4.1.1
2001-03-30 Added TERM cystathionine-gamma-lyase

Term

Timestamp Action Category Detail
2003-09-09 Updated TERM cystathionine gamma-lyase activity
2003-03-19 Updated TERM cystathionine-gamma-lyase activity
2002-02-06 Updated TERM cystathionine-gamma-lyase
2001-04-03 Updated TERM cystathionine-gamma-lyase
2001-03-30 Added TERM cystathionine-gamma-lyase

Definition/synonyms

Timestamp Action Category Detail
2011-09-16 Deleted DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2011-09-16 Added DEFINITION Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
2011-09-16 Deleted SYNONYM cystine desulfhydrase activity
2011-09-16 Deleted SYNONYM homoserine deaminase-cystathionase activity
2011-09-16 Deleted SYNONYM gamma-cystathionase activity
2011-09-16 Deleted SYNONYM cystathionase activity
2011-09-16 Deleted SYNONYM cysteine desulfhydrase activity
2011-09-16 Deleted SYNONYM cystathioninase activity
2011-09-16 Added SYNONYM L-cystathionine cysteine-lyase (deaminating)
2011-09-16 Added SYNONYM homoserine dehydratase activity
2011-09-16 Added SYNONYM homoserine deaminase activity
2011-09-16 Added SYNONYM gamma-cystathionase activity
2011-09-16 Added SYNONYM homoserine deaminase-cystathionase activity
2011-09-16 Deleted SYNONYM homoserine dehydratase activity
2011-09-16 Deleted SYNONYM gamma-CTL
2011-09-16 Deleted SYNONYM cystalysin
2011-09-16 Deleted SYNONYM homoserine deaminase activity
2011-09-16 Deleted SYNONYM L-cystathionine cysteine-lyase (deaminating)
2008-05-13 Added DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2007-11-08 Added SYNONYM L-cystathionine cysteine-lyase (deaminating)
2007-11-08 Added SYNONYM L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)
2007-11-08 Added SYNONYM cystalysin
2007-11-08 Added SYNONYM gamma-CTL
2007-11-08 Added SYNONYM homoserine deaminase-cystathionase activity
2007-09-06 Added SYNONYM cystathionase activity
2007-09-06 Added SYNONYM cystathioninase activity
2007-09-06 Added SYNONYM cystine desulfhydrase activity
2007-09-06 Added SYNONYM gamma-cystathionase activity
2007-09-06 Added SYNONYM homoserine deaminase activity
2007-09-06 Added SYNONYM homoserine dehydratase activity
2007-08-09 Added SYNONYM cysteine desulfhydrase activity
2007-08-09 Deleted SYNONYM cysteine desulfhydrase activity
2004-12-03 Deleted SYNONYM cysteine desulfurase
2004-04-19 Added SYNONYM cysteine desulfhydrase activity
2004-04-19 Added SYNONYM cysteine desulfurase
2004-04-16 Deleted SYNONYM cysteine desulfhydrase activity
2004-04-16 Deleted SYNONYM cysteine desulfurase
2004-03-17 Added SYNONYM cysteine desulfhydrase activity
2004-03-17 Added SYNONYM cysteine desulfurase
2003-10-30 Updated DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate.
2002-11-27 Added DEFINITION Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + ammonia + 2-oxobutanoate.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016846 (carbon-sulfur lyase activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:24918
2011-09-16 Added XREF KEGG:R01001
2004-12-03 Deleted XREF EC:4.4.1.-
2004-03-17 Added XREF EC:4.4.1.-
2003-10-27 Added XREF MetaCyc:CYSTAGLY-RXN
2001-03-30 Added XREF EC:4.4.1.1

Other

Timestamp Action Category Detail
2004-03-17 Added SECONDARY GO:0016225 (cysteine desulfhydrase activity)
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