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GO:0004090 carbonyl reductase (NADPH) activity

Term Information

ID GO:0004090
Name carbonyl reductase (NADPH) activity
Ontology Molecular Function
Definition Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
GONUTS GO:0004090 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact NADPH-dependent carbonyl reductase activity
related aldehyde reductase I activity
related ALR3
exact secondary-alcohol:NADP+ oxidoreductase activity
exact NADPH2-dependent carbonyl reductase activity
exact carbonyl reductase activity
narrow prostaglandin 9-ketoreductase activity
narrow xenobiotic ketone reductase activity
related aldehyde reductase 1
exact nonspecific NADPH-dependent carbonyl reductase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.1.1.184
MetaCyc CARBONYL-REDUCTASE-NADPH-RXN
RHEA 19260

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004090:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004090. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004090 based on the entire annotation set Co-occurrence statistics for GO:0004090 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:19260
2009-05-21 Deleted XREF MetaCyc:CARBONYL-REDUCTASE-(NADPH)-RXN
2009-05-21 Added XREF MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2007-11-08 Added SYNONYM ALR3
2007-11-08 Added SYNONYM NADPH2-dependent carbonyl reductase activity
2007-11-08 Added SYNONYM aldehyde reductase 1
2007-11-08 Added SYNONYM carbonyl reductase activity
2007-11-08 Added SYNONYM nonspecific NADPH-dependent carbonyl reductase activity
2007-11-08 Added SYNONYM secondary-alcohol:NADP+ oxidoreductase activity
2007-09-06 Added SYNONYM NADPH-dependent carbonyl reductase activity
2007-09-06 Added SYNONYM aldehyde reductase I activity
2007-09-06 Added SYNONYM prostaglandin 9-ketoreductase activity
2007-09-06 Added SYNONYM xenobiotic ketone reductase activity
2003-10-27 Added XREF MetaCyc:CARBONYL-REDUCTASE-(NADPH)-RXN
2003-03-19 Updated TERM carbonyl reductase (NADPH) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
2002-02-06 Updated TERM carbonyl reductase (NADPH)
2001-04-03 Updated TERM carbonyl reductase (NADPH)
2001-03-30 Added XREF EC:1.1.1.184
2001-03-30 Added TERM carbonyl reductase (NADPH)

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM carbonyl reductase (NADPH) activity
2002-02-06 Updated TERM carbonyl reductase (NADPH)
2001-04-03 Updated TERM carbonyl reductase (NADPH)
2001-03-30 Added TERM carbonyl reductase (NADPH)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
2007-11-08 Added SYNONYM ALR3
2007-11-08 Added SYNONYM NADPH2-dependent carbonyl reductase activity
2007-11-08 Added SYNONYM aldehyde reductase 1
2007-11-08 Added SYNONYM carbonyl reductase activity
2007-11-08 Added SYNONYM nonspecific NADPH-dependent carbonyl reductase activity
2007-11-08 Added SYNONYM secondary-alcohol:NADP+ oxidoreductase activity
2007-09-06 Added SYNONYM NADPH-dependent carbonyl reductase activity
2007-09-06 Added SYNONYM aldehyde reductase I activity
2007-09-06 Added SYNONYM prostaglandin 9-ketoreductase activity
2007-09-06 Added SYNONYM xenobiotic ketone reductase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:19260
2009-05-21 Deleted XREF MetaCyc:CARBONYL-REDUCTASE-(NADPH)-RXN
2009-05-21 Added XREF MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN
2003-10-27 Added XREF MetaCyc:CARBONYL-REDUCTASE-(NADPH)-RXN
2001-03-30 Added XREF EC:1.1.1.184
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