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GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

Term Information

ID GO:0004088
Name carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
GONUTS GO:0004088 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
exact CPS activity
exact GD-CPSase activity
exact carbamoyl phosphate synthetase activity
exact carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity
exact carbamoylphosphate synthetase II activity
exact carbamyl phosphate synthetase (glutamine) activity
exact glutamine-dependent carbamoyl-phosphate synthase activity
exact glutamine-dependent carbamyl phosphate synthetase activity
exact carbamoyl-phosphate synthase (glutamine-hydrolysing) activity
exact carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity
exact carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity
exact hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 6.3.5.5
MetaCyc CARBPSYN-RXN
RHEA 24654

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0004086 carbamoyl-phosphate synthase activity CONSIDER GO:0004088

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004088:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004088. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004088 based on the entire annotation set Co-occurrence statistics for GO:0004088 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:24654
2011-09-04 Deleted RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2008-04-01 Updated RELATION is a GO:0016884 (carbon-nitrogen ligase activity, with glutamine as amido-N-donor)
2008-04-01 Updated RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)
2007-12-14 Added SYNONYM carbamoyl-phosphate synthase (glutamine-hydrolysing) activity
2007-12-14 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity
2007-12-14 Added SYNONYM carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity
2007-12-14 Added SYNONYM hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity
2007-09-06 Added SYNONYM CPS activity
2007-09-06 Added SYNONYM GD-CPSase activity
2007-09-06 Added SYNONYM carbamoyl phosphate synthetase activity
2007-09-06 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity
2007-09-06 Added SYNONYM carbamoylphosphate synthetase II activity
2007-09-06 Added SYNONYM carbamyl phosphate synthetase (glutamine) activity
2007-09-06 Added SYNONYM glutamine-dependent carbamoyl-phosphate synthase activity
2007-09-06 Added SYNONYM glutamine-dependent carbamyl phosphate synthetase activity
2007-09-06 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2007-08-09 Deleted SYNONYM carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
2007-08-09 Added SYNONYM carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
2007-08-09 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2007-08-09 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2007-05-06 Added SYNONYM carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
2004-04-19 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2004-04-16 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2003-10-27 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2003-10-27 Added XREF MetaCyc:CARBPSYN-RXN
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2003-08-21 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2003-03-19 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + carbon dioxide + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2002-06-23 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2002-02-06 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-04-03 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-03-30 Added XREF EC:6.3.5.5
2001-03-30 Added TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
2002-02-06 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-04-03 Updated TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)
2001-03-30 Added TERM carbamoyl-phosphate synthase (glutamine-hydrolyzing)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2007-12-14 Added SYNONYM carbamoyl-phosphate synthase (glutamine-hydrolysing) activity
2007-12-14 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity
2007-12-14 Added SYNONYM carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity
2007-12-14 Added SYNONYM hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity
2007-09-06 Added SYNONYM CPS activity
2007-09-06 Added SYNONYM GD-CPSase activity
2007-09-06 Added SYNONYM carbamoyl phosphate synthetase activity
2007-09-06 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity
2007-09-06 Added SYNONYM carbamoylphosphate synthetase II activity
2007-09-06 Added SYNONYM carbamyl phosphate synthetase (glutamine) activity
2007-09-06 Added SYNONYM glutamine-dependent carbamoyl-phosphate synthase activity
2007-09-06 Added SYNONYM glutamine-dependent carbamyl phosphate synthetase activity
2007-09-06 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2007-08-09 Deleted SYNONYM carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
2007-08-09 Added SYNONYM carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
2007-08-09 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2007-08-09 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2007-05-06 Added SYNONYM carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
2004-04-19 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2004-04-16 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2003-10-27 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2003-08-21 Deleted SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + carbon dioxide + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2002-06-23 Added SYNONYM carbamoyl-phosphate synthetase (glutamine-hydrolyzing)

Relationships

Timestamp Action Category Detail
2011-09-04 Deleted RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)
2008-04-01 Updated RELATION is a GO:0016884 (carbon-nitrogen ligase activity, with glutamine as amido-N-donor)
2008-04-01 Updated RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:24654
2003-10-27 Added XREF MetaCyc:CARBPSYN-RXN
2001-03-30 Added XREF EC:6.3.5.5
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